Rome2Rio

How to get fromWheeling to St. Louisby train, plane, train (Amtrak), bus (Flixbus), car, subway, or bus

Find Transport to St. Louis

See all options

There are 6 ways to get from Wheeling to St. Louis by train, plane, train (Amtrak), bus (Flixbus), car, subway, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly

    best
    1. Take the train from Wheeling to O'Hare Transfertrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    3h 29m
    $277–707

  2. Drive 304.5 mi

    cheapest
    1. Drive from Wheeling to St. Louiscar car 304.5 mi
    5h 15m
    $56–81

  3. Train

    1. Take the train from Wheeling to Chicago Union Stationtrain train Ncs
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    6h 41m
    $95–196

  4. Bus

    1. Take the bus from O'Hare Multi-Modal Facility to Illinois Terminalbus bus Chicago Area to Champaign SOUTH / ...
    2. Take the bus from Champaign Intermodal Trans Ctr to St Louis Bus Stationbus bus FlixBus N2521 / ...
    10h 19m
    $77–114

  5. Train, subway to Chicago Midway International Airport, fly

    1. Take the train from Wheeling to Chicago Union Stationtrain train
    2. Take the subway from LaSalle/Van Buren to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    4h 48m
    $90–564

  6. Bus to General Mitchell International Airport, fly

    1. Take the bus from Multi-Modal/Rental Car Facility to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    4h 58m
    $522–895

Wheeling to St. Louis by train

Calendar35Weekly Trains
Duration6h 41mAverage Duration
Ticket$95Cheapest Price
See schedules

Questions & Answers

Map of how to get from Wheeling to St. Louis.ExpandLaunch map view
  • Distance: 285.5 mi
  • Duration: 3h 29m

What companies run services between Wheeling, IL, USA and St. Louis, MO, USA?

You can take a train from Wheeling to St. Louis via Chicago Union Station in around 6h 41m. Alternatively, you can take a bus from Dundee/Northgate to St Louis Bus Station via Des Plaines Metra Station, O'Hare MMF Bay 9, O'Hare Multi-Modal Facility, Illinois Terminal, and Champaign Intermodal Trans Ctr in around 10h 19m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

More Questions & Answers