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How to get fromWheeling to Knoxvilleby bus, plane, car, bus (Flixbus), or train

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There are 7 ways to get from Wheeling to Knoxville by bus, plane, car, bus (Flixbus), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the bus from Wheeling Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Mcghee Tyson Airport (TYS)plane plane PIT - TYS
    7h 42m
    $197–866

  2. Drive 430.6 mi

    cheapest
    1. Drive from Wheeling to Knoxvillecar car 430.6 mi
    9h 16m
    $79–114

  3. Bus

    1. Take the bus from Wheeling to New York, NYbus bus Dayton
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    20h 5m
    $245–270

  4. Bus to Pittsburgh International Airport, fly to Nashville, drive

    1. Take the bus from Wheeling Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Nashville (BNA)plane plane PIT - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    8h 4m
    $542–1,096

  5. Bus, bus to Morgantown Municipal Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Wheeling Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Take the bus from Pittsburgh Greyhound to Westover Terminalbus bus
    3. Fly from Morgantown Municipal Airport (MGW) to Mcghee Tyson Airport (TYS)plane plane MGW - TYS
    11h 1m
    $178–767

  6. Bus via Farragut

    1. Take the bus from Wheeling Bus Stop to New York Midtownbus bus FlixBus N2642
    2. Take the bus from New York to Knoxvillebus bus Nyc
    24h 23m
    $261–380

  7. Bus, train

    1. Take the bus from Wheeling Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Take the train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    25h 12m
    $277–469

Pittsburgh International Airport (PIT) to Mcghee Tyson Airport (TYS) flights

Calendar125Weekly Planes
Duration4h 29mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from Wheeling to Knoxville.ExpandLaunch map view
  • Distance: 470.4 mi
  • Duration: 7h 42m

What companies run services between Wheeling, WV, USA and Knoxville, TN, USA?

You can take a bus from Wheeling to Knoxville via New York, NY and Knoxville, TN in around 20h 5m.

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Train operators
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