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How to get fromWheeling to Lexingtonby bus, plane, or car

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There are 6 ways to get from Wheeling to Lexington by bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Louisville International Airport, drive

    best
    1. Take the bus from Wheeling Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Louisville International Airport (SDF)plane plane PIT - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    6h 43m
    $126–667

  2. Bus, drive via Columbus

    cheapest
    1. Take the bus from Wheeling Bus Stop to Columbusbus bus
    2. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    12h 34m
    $54–121

  3. Drive 290.8 mi

    1. Drive from Wheeling to Lexingtoncar car 290.8 mi
    6h 22m
    $54–77

  4. Bus, fly to Covington, drive

    1. Take the bus from Wheeling Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Covington (CVG)plane plane PIT - CVG
    3. Drive from Covington (CVG) to Lexingtoncar car
    8h 32m
    $337–718

  5. Bus, fly to Blue Grass Airport

    1. Take the bus from Wheeling Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Blue Grass Airport (LEX)plane plane PIT - LEX
    9h 41m
    $154–898

  6. Bus, drive

    1. Take the bus from Wheeling Bus Stop to Cincinnatibus bus
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    13h 24m
    $65–139

Pittsburgh International Airport (PIT) to Louisville International Airport (SDF) flights

Calendar10Weekly Planes
Duration2h 59mAverage Duration
Ticket$103Cheapest Price
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Questions & Answers

Map of how to get from Wheeling to Lexington.ExpandLaunch map view
  • Distance: 488.6 mi
  • Duration: 6h 43m

What companies run services between Wheeling, WV, USA and Lexington, KY, USA?

There is no direct connection from Wheeling to Lexington. However, you can take the bus to Pittsburgh Intermodal Station, walk to Pittsburgh Greyhound, take the bus to Pittsburgh Airport PIT, walk to Pittsburgh International Airport (PIT) airport, fly to Louisville International Airport (SDF), then drive to Lexington. Alternatively, you can take a bus from Wheeling Bus Stop to Lexington via Columbus - Downtown - Mound St, Louisville, KY Bus Station, Roy Wilkins @ W Broadway, Chestnut @ 8th, S 5th @ W Jefferson, and Middletown Station @ Target in around 12h 34m.

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