There are 7 ways to get from Wiesbaden to Palermo by plane, train (Trenitalia), car, car ferry, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Palermo Airport
best- Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane FRA - PMO
5h 48m€82–230Train
- Take the train from Frankfurt to Basel SBBtrain 43
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
25h 46m€259–565Drive, car ferry
- Drive from Wiesbaden to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
27h 18m€250–367Bus
- Take the bus from Wiesbaden Gartenfeldstraße P+R to Palermo Piazza Cairolibus
36h 46m€290–400Train to Cologne Bonn Airport, fly to Palermo Airport
- Take the train from Wiesbaden Hauptbahnhof to Flughafen Köln/Bonn Bftrain
- Fly from Cologne Bonn Airport (CGN) to Palermo Airport (PMO)plane CGN - PMO
6h 22m€93–363Fly Frankfurt to Catania–Fontanarossa Airport, bus
- Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane FRA - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus
8h 29m€95–252Train, bus
- Take the train from Frankfurt to Basel SBBtrain 43
- Take the train from Basel SBB to Domodossolatrain Ec
- Take the bus from Domodossola to Rho Fiera Milanobus Re4
- Take the train from Milano Rogoredo to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
26h 30m
Frankfurt (FRA) to Palermo Airport (PMO) flights
Comparing Your Travel Options
The cheapest way to get from Wiesbaden to Palermo is to fly which costs €80 - €230 and takes 5h 48m.
The fastest way to get from Wiesbaden to Palermo is to fly which takes 5h 48m and costs €80 - €230.
Yes, there is a direct bus departing from Wiesbaden Gartenfeldstraße P+R and arriving at Palermo Piazza Cairoli. Services depart once a week, and operate Wednesday and Saturday. The journey takes approximately 36h 46m.
No, there is no direct train from Wiesbaden to Palermo. However, there are services departing from Wiesbaden Hauptbahnhof and arriving at Palermo Centrale via Frankfurt, Basel SBB, Lugano, Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 25h 46m.
The distance between Wiesbaden and Palermo is 1433 km.
The best way to get from Wiesbaden to Palermo without a car is to train which takes 25h 46m and costs €250 - €600.
It takes approximately 5h 48m to get from Wiesbaden to Palermo, including transfers.
Wiesbaden to Palermo bus services, operated by Onebus, depart from Wiesbaden Gartenfeldstraße P+R station.
Wiesbaden to Palermo train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Wiesbaden to Palermo is to fly which takes 5h 48m and costs €80 - €230. Alternatively, you can train, which costs €250 - €600 and takes 25h 46m, you could also bus, which costs €290 - €400 and takes 36h 46m.
What companies run services between Wiesbaden, Germany and Palermo, Italy?
Lufthansa and ITA Airways fly from Frankfurt (FRA) to Palermo Airport (PMO) once daily. Alternatively, you can take a train from Wiesbaden Hauptbahnhof to Palermo Centrale via Frankfurt, Basel SBB, Lugano, Milano Centrale, and Roma Termini in around 25h 46m.
- Website
- ita-airways.com
Flights from Frankfurt to Palermo Airport via Milan Linate
- Ave. Duration
- 5h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €95–200
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €70–260
Flights from Frankfurt to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- €60–200
- Website
- lufthansa.com
Flights from Frankfurt to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Thursday and Saturday
- Estimated price
- €75–280
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €70–260
- Website
- ryanair.com
Flights from Cologne Bonn Airport to Palermo Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- €45–150
Flights from Cologne Bonn Airport to Palermo Airport via Bologna
- Ave. Duration
- 5h
- When
- Friday
- Estimated price
- €45–150
- Website
- eurowings.com
Flights from Cologne Bonn Airport to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Saturday
- Estimated price
- €100–230
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Basel SBB
- Ave. Duration
- 2h 57m
- Frequency
- Hourly
- Estimated price
- €50–110
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Wiesbaden Hauptbahnhof to Flughafen Köln/Bonn Bf
- Ave. Duration
- 1h 8m
- Frequency
- 5 times a week
- Estimated price
- €25–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Basel SBB
- Ave. Duration
- 2h 57m
- Frequency
- Hourly
- Estimated price
- €50–110
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €80–130
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €25–40
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Domodossola
- Ave. Duration
- 2h 42m
- Frequency
- Twice daily
- Estimated price
- €80–120
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 (0) 7531 915109
- [email protected]
- Website
- SBB GmbH
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- SBB GmbH
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €65–110
- Website
- Italo Treno
Train from Milano Rogoredo to Roma Termini
- Ave. Duration
- 3h 34m
- Frequency
- Every 30 minutes
- Estimated price
- €65–110
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- 4 times a day
- Estimated price
- €95–170
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- 4 times a day
- Estimated price
- €95–170
- Website
- Trenitalia Intercity
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Rogoredo to Roma Termini
- Ave. Duration
- 4h 14m
- Frequency
- Every 4 hours
- Estimated price
- €75–140
- Website
- Trenitalia Frecce
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Wiesbaden Gartenfeldstraße P+R to Palermo Piazza Cairoli
- Ave. Duration
- 36h 46m
- Frequency
- Once a week
- Estimated price
- €290–400
- Website
- Onebus
- Phone
- 800 21 10 20
- [email protected]
- Website
- SAIS Autolinee
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Estimated price
- €11–16
- Schedules at
- SAIS Autolinee
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- €18–27
- Website
- Flixbus
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Bus from Domodossola to Rho Fiera Milano
- Ave. Duration
- 1h 25m
- Frequency
- Every 2 hours
- Website
- Trenord
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 19h 30m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Wiesbaden to Palermo bus services, operated by Onebus, arrive at Palermo Piazza Cairoli station.
Wiesbaden to Palermo train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Book your Wiesbaden to Palermo train tickets online with Omio.
Book your Wiesbaden to Palermo bus tickets online with Omio.
There are 6022+ hotels available in Palermo.

















































