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How to get fromWilkes-Barre to Chicagoby plane, bus (Flixbus), bus, train, car, or bus (Greyhound)

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There are 5 ways to get from Wilkes-Barre to Chicago by plane, bus (Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Wilkes-Barre/Scranton International Airport (AVP) to Chicago O'Hare International Airport (ORD)plane plane AVP - ORD
    3h 24m
    $130–468

  2. Drive 683.9 mi

    cheapest
    1. Drive from Wilkes-Barre to Chicagocar car 683.9 mi
    11h 11m
    $125–181

  3. Bus

    1. Take the bus from Wilkes-Barre to State Collegebus bus Fab815
    2. Take the bus from State College Regional Airport to Chicago Bus Stationbus bus FlixBus N2641 / ...
    16h 24m
    $146–253

  4. Bus, train

    1. Take the bus from Scranton Bus Station to Syracuse Bus Stationbus bus Greyhound US0215
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train Lake Shore Limited
    18h 22m
    $240–509

  5. Bus via Baltimore

    1. Take the bus from Wilkes Barre, Pa to Harrisburg, Pabus bus 771
    2. Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus
    24h 50m
    $143–305

Wilkes-Barre to Chicago by bus

Calendar7Weekly Buses
Duration16h 24mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

Map of how to get from Wilkes-Barre to Chicago.ExpandLaunch map view
  • Distance: 658.7 mi
  • Duration: 3h 24m

What companies run services between Wilkes-Barre, PA, USA and Chicago, IL, USA?

American Airlines and United Airlines fly from Wilkes-Barre/Scranton International Airport (AVP) to Chicago O'Hare International Airport (ORD) every 4 hours. Alternatively, you can take a bus from Wilkes-Barre to Chicago Bus Station via State College Regional Airport in around 16h 24m.

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