Rome2Rio

How to get fromWilkes-Barre to Florenceby plane, bus (Greyhound, Flixbus), bus, train, or car

Find Transport to Florence

See all options

There are 6 ways to get from Wilkes-Barre to Florence by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Wilkes-Barre/Scranton International Airport (AVP) to Florence Regional Airport (FLO)plane plane AVP - FLO
    5h 58m
    $148–566

  2. Bus via Washington

    cheapest
    1. Take the bus from Wilkes Barre, Pa to Harrisburg, Pabus bus 771
    2. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus
    4. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    16h 24m
    $96–217

  3. Bus, train

    1. Take the bus from Wilkes-Barre to Philadelphia 30th St Stationbus bus Wilkes-Barre
    2. Take the train from 30th Street Station to Florence Stationtrain train Palmetto / ...
    18h 1m
    $216–441

  4. Drive 612.2 mi

    1. Drive from Wilkes-Barre to Florencecar car 612.2 mi
    10h 51m
    $112–162

  5. Bus

    1. Take the bus from Wilkes-Barre to Port Authority Bus Terminalbus bus Wilkes-Barre
    2. Take the bus from New York, NY to Florence, SCbus bus Nyc
    16h 58m
    $158–232

  6. Bus, train via Harrisburg

    1. Take the bus from Wilkes Barre, Pa to Harrisburg, Pabus bus 771
    2. Take the train from Harrisburg to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Florence Stationtrain train
    19h 18m
    $212–492

Wilkes-Barre to Florence by bus

Calendar7Weekly Buses
Duration16h 24mAverage Duration
Ticket$96Cheapest Price
See schedules

Questions & Answers

Map of how to get from Wilkes-Barre to Florence.ExpandLaunch map view
  • Distance: 553.2 mi
  • Duration: 5h 58m

What companies run services between Wilkes-Barre, PA, USA and Florence, SC, USA?

American Airlines flies from Wilkes-Barre/Scranton International Airport (AVP) to Florence Regional Airport (FLO) 5 times a day. Alternatively, you can take a bus from Wilkes Barre, Pa to Florence Bus Station via Harrisburg Bus Station, Washington Union Station, and Raleigh Bus Station in around 16h 24m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers