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How to get fromWilkes-Barre to Knoxvilleby plane, bus, car, or bus (Flixbus)

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There are 5 ways to get from Wilkes-Barre to Knoxville by plane, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Wilkes-Barre/Scranton International Airport (AVP) to Mcghee Tyson Airport (TYS)plane plane AVP - TYS
    4h 50m
    $278–1,083

  2. Drive 640 mi

    cheapest
    1. Drive from Wilkes-Barre to Knoxvillecar car 640 mi
    10h 39m
    $117–169

  3. Bus

    1. Take the bus from Wilkes-Barre to Port Authority Bus Terminalbus bus Wilkes-Barre
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    16h 52m
    $205–254

  4. Bus via Farragut

    1. Take the bus from Wilkes-Barre to New Yorkbus bus Eze 11Ampa / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    19h 18m
    $230–319

  5. Bus via Allentown

    1. Take the bus from Wilkes-Barre to Allentown Transportation Centerbus bus
    2. Take the bus from Allentown to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    23h 25m
    $163–208

Wilkes-Barre/Scranton International Airport (AVP) to Mcghee Tyson Airport (TYS) flights

Calendar43Weekly Planes
Duration6h 1mAverage Duration
Ticket$174Cheapest Price
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Questions & Answers

Map of how to get from Wilkes-Barre to Knoxville.ExpandLaunch map view
  • Distance: 611.2 mi
  • Duration: 4h 50m

What companies run services between Wilkes-Barre, PA, USA and Knoxville, TN, USA?

United Airlines and American Airlines fly from Wilkes-Barre/Scranton International Airport (AVP) to Mcghee Tyson Airport (TYS) every 4 hours. Alternatively, you can take a bus from Wilkes-Barre to Knoxville via Port Authority Bus Terminal, 42 St-Bryant Park, East Broadway, New York, NY, and Knoxville, TN in around 16h 52m.

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