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How to get fromWilkes-Barre to Louisvilleby plane, bus (Flixbus), car, or bus (Greyhound)

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There are 4 ways to get from Wilkes-Barre to Louisville by plane, bus (Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Wilkes-Barre/Scranton International Airport (AVP) to Louisville International Airport (SDF)plane plane AVP - SDF
    5h 33m
    $184–766

  2. Bus via Columbus

    cheapest
    1. Take the bus from Wilkes Barre, Pa to Harrisburg, Pabus bus 771
    2. Take the bus from Harrisburg Bus Station to Columbusbus bus
    3. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    17h 45m
    $98–232

  3. Bus

    1. Take the bus from Wilkes Barre, Pa to Harrisburg, Pabus bus 771
    2. Take the bus from Harrisburg Bus Station to Cincinnatibus bus
    3. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    17h 42m
    $112–250

  4. Drive 646.3 mi

    1. Drive from Wilkes-Barre to Louisvillecar car 646.3 mi
    11h 27m
    $118–171

Wilkes-Barre to Louisville by bus and foot

Calendar7Weekly Services
Duration17h 42mAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

Map of how to get from Wilkes-Barre to Louisville.ExpandLaunch map view
  • Distance: 591.6 mi
  • Duration: 5h 33m

What companies run services between Wilkes-Barre, PA, USA and Louisville, KY, USA?

United Airlines and American Airlines fly from Wilkes-Barre/Scranton International Airport (AVP) to Louisville International Airport (SDF) 5 times a day. Alternatively, you can take a bus from Wilkes Barre, Pa to Louisville, KY Bus Station via Harrisburg Bus Station, Cincinnati, Vine St & Martin Luther King Dr, Race St & Court St, and Cincinnati - Downtown in around 17h 42m.

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