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How to get fromWilliamsport to Des Moinesby bus, plane, bus (Flixbus, Greyhound), train, or car

Find Transport to Des Moines

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There are 6 ways to get from Williamsport to Des Moines by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Penn State University Park Airport, fly

    best
    1. Take the bus from Williamsport to State Collegebus bus
    2. Fly from Penn State University Park Airport (SCE) to Des Moines (DSM)plane plane SCE - DSM
    6h 41m
    $113–493

  2. Bus

    1. Take the bus from Williamsport to State Collegebus bus
    2. Take the bus from State College Regional Airport to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    24h 20m
    $165–295

  3. Bus, train

    1. Take the bus from Williamsport to State Collegebus bus
    2. Take the bus from State College Regional Airport to Pittsburgh Intermodal Stationbus bus
    3. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    5. Take the bus from Galesburg to Des Moinesbus bus
    25h 22m
    $215–515

  4. Drive  928.3 mi

    1. Drive from Williamsport to Des Moinescar car 928.3 mi
    15h 24m
    $170–245

  5. Bus to Wilkes-Barre/Scranton International Airport, fly

    1. Take the bus from Williamsport to Wilkes-Barrebus bus
    2. Fly from Wilkes-Barre/Scranton International Airport (AVP) to Des Moines (DSM)plane plane AVP - DSM
    8h 17m
    $210–801

  6. Bus to Harrisburg International Airport, fly

    1. Take the bus from Williamsport, Pa to Harrisburg, Pabus bus
    2. Fly from Harrisburg International Airport (MDT) to Des Moines (DSM)plane plane MDT - DSM
    8h 57m
    $125–518

Williamsport to Des Moines by bus

Calendar7Weekly Buses
Duration24h 20mAverage Duration
Ticket$165Cheapest Price
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Comparing Your Travel Options

Map of how to get from Williamsport to Des Moines.ExpandLaunch map view
  • Distance: 888.3 mi
  • Duration: 6h 41m

What companies run services between Williamsport, Lycoming County, PA, USA and Des Moines, IA, USA?

You can take a bus from Williamsport to Des Moines via State College Regional Airport and Chicago Bus Station in around 24h 20m.

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