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How to get fromWilliamsport to Des Moinesby bus, plane, bus (Flixbus, Greyhound), train, or car

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There are 6 ways to get from Williamsport to Des Moines by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Penn State University Park Airport, fly

    best
    1. Take the bus from Williamsport to State Collegebus bus
    2. Fly from Penn State University Park Airport (SCE) to Des Moines (DSM)plane plane SCE - DSM
    6h 31m
    $166–758

  2. Bus

    1. Take the bus from Williamsport to State Collegebus bus
    2. Take the bus from State College Regional Airport to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    22h 5m
    $169–307

  3. Bus, train

    1. Take the bus from Williamsport to State Collegebus bus
    2. Take the bus from State College Regional Airport to Pittsburgh Intermodal Stationbus bus
    3. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    5. Take the bus from Galesburg to Des Moinesbus bus
    25h 22m
    $271–572

  4. Drive 928.3 mi

    1. Drive from Williamsport to Des Moinescar car 928.3 mi
    15h 24m
    $170–245

  5. Bus to Wilkes-Barre/Scranton International Airport, fly

    1. Take the bus from Williamsport to Wilkes-Barrebus bus
    2. Fly from Wilkes-Barre/Scranton International Airport (AVP) to Des Moines (DSM)plane plane AVP - DSM
    8h 8m
    $284–1,034

  6. Bus to Harrisburg International Airport, fly

    1. Take the bus from Williamsport, Pa to Harrisburg, Pabus bus
    2. Fly from Harrisburg International Airport (MDT) to Des Moines (DSM)plane plane MDT - DSM
    8h 57m
    $339–1,576

Williamsport to Des Moines by bus

Calendar7Weekly Buses
Duration22h 5mAverage Duration
Ticket$169Cheapest Price
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Questions & Answers

Map of how to get from Williamsport to Des Moines.ExpandLaunch map view
  • Distance: 888.3 mi
  • Duration: 6h 31m

What companies run services between Williamsport, Lycoming County, PA, USA and Des Moines, IA, USA?

You can take a bus from Williamsport to Des Moines via State College Regional Airport and Chicago Bus Station in around 22h 5m.

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Train operators
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