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How to get fromWilmette to St. Louisby train (Amtrak), bus (Flixbus), car, train, subway, plane, or bus

Find Transport to St. Louis

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There are 6 ways to get from Wilmette to St. Louis by train (Amtrak), bus (Flixbus), car, train, subway, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    6h 26m
    $77–168

  2. Bus (Flixbus)

    cheapest
    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    8h 45m
    $48–72

  3. Drive  306.1 mi

    1. Drive from Wilmette to St. Louiscar car 306.1 mi
    5h 14m
    $56–81

  4. Train, subway to Chicago Midway International Airport, fly

    1. Take the train from Wilmette to Chicago OTCtrain train
    2. Take the subway from Clark/Lake to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    4h 27m
    $79–513

  5. Train to Chicago O'Hare International Airport, fly

    1. Take the train from Wilmette to Clybourntrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    4h 32m
    $330–714

  6. Train, bus to General Mitchell International Airport, fly

    1. Take the train from Wilmette to Kenoshatrain train
    2. Take the bus from Metro Train Station - 13th Avenue and 54th Street to Mitchell Airportbus bus
    3. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    6h 16m
    $495–874

Wilmette to St. Louis by train and bus (Amtrak)

Calendar38Weekly Services
Duration6h 26mAverage Duration
Ticket$77Cheapest Price
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Comparing Your Travel Options

Map of how to get from Wilmette to St. Louis.ExpandLaunch map view
  • Distance: 295.6 mi
  • Duration: 6h 26m

What companies run services between Wilmette, IL, USA and St. Louis, MO, USA?

Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $70–160 and the journey takes 4h 46m. Alternatively, Flixbus USA operates a bus from Chicago Bus Station to St Louis Bus Station twice daily. Tickets cost $45–70 and the journey takes 5h 55m.

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