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How to get fromWilmington to Buffaloby train, plane, bus, train (Amtrak), car, or bus (Flixbus)

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There are 9 ways to get from Wilmington to Buffalo by train, plane, bus, train (Amtrak), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Philadelphia International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Wilmington to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane plane PHL - BUF
    4h 25m
    $106–1,224

  2. Drive 355.5 mi

    cheapest
    1. Drive from Wilmington to Buffalocar car 355.5 mi
    7h 10m
    $65–94

  3. Train, bus

    1. Take the train from Wilmington to Gray 30th St Stationtrain train Wil
    2. Take the bus from Philadelphia 30th St Station to Scrantonbus bus
    3. Take the bus from Scranton Bus Station to Buffalobus bus
    11h 22m
    $93–158

  4. Train (Amtrak)

    1. Take the train from Wilmington to Ny Moynihan Train Hall At Penn Stationtrain train Northeast Regional / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    11h 28m
    $157–907

  5. Train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Wilmington to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane plane BWI - BUF
    4h 13m
    $100–1,165

  6. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Wilmington to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    4h 52m
    $105–557

  7. Train to Ronald Reagan Washington National Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Wilmington to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Buffalo Niagara International Airport (BUF)plane plane DCA - BUF
    5h 14m
    $151–1,447

  8. Train to Philadelphia International Airport, fly to Rochester, bus

    1. Take the train from Wilmington to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane plane PHL - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 38m
    $138–1,288

  9. Bus

    1. Take the bus from Wilmington, DE - 3 W 4th St. to Midtown - 400 8th Avebus bus New York to Wilmington
    2. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    11h 42m
    $97–157

Wilmington to Buffalo by train and bus

Calendar7Weekly Services
Duration11h 22mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Wilmington to Buffalo.ExpandLaunch map view
  • Distance: 325.7 mi
  • Duration: 4h 25m

What companies run services between Wilmington, DE, USA and Buffalo, NY, USA?

You can take a train from Wilmington to Buffalo via Ny Moynihan Train Hall At Penn Station in around 11h 28m. Alternatively, you can take a bus from Wilmington, DE - 3 W 4th St. to Buffalo via Midtown - 400 8th Ave and New York Midtown in around 11h 42m.

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