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How to get fromWilmington to Durhamby train, plane, bus, train (Amtrak), car, subway, or bus (Greyhound, Flixbus)

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There are 11 ways to get from Wilmington to Durham by train, plane, bus, train (Amtrak), car, subway, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Philadelphia International Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus

    best
    1. Take the train from Wilmington to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Raleigh-Durham International Airport (RDU)plane plane PHL - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    4. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    4h 54m
    $90–921

  2. Bus via Washington

    cheapest
    1. Take the bus from Wilmington Bus Station to Washington Union Stationbus bus Greyhound US0305 / ...
    2. Take the bus from Washington Union Station to Durhambus bus FlixBus N2471 / ...
    9h 4m
    $56–115

  3. Bus

    1. Take the bus from Wilmington, DE - 3 W 4th St to Baltimore, MDbus bus Wilmington to Baltimore
    2. Take the bus from Baltimore, MD to Durhambus bus Nyc
    8h 56m
    $66–97

  4. Train via Washington (Amtrak)

    1. Take the train from Wilmington to Washington Union Stationtrain train Northeast Regional / ...
    2. Take the train from Washington Union Station to Durham Amtrak Stationtrain train Carolinian
    9h 25m
    $125–831

  5. Drive 365.5 mi

    1. Drive from Wilmington to Durhamcar car 365.5 mi
    6h 27m
    $67–97

  6. Train to Baltimore-Washington International Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Wilmington to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Raleigh-Durham International Airport (RDU)plane plane BWI - RDU
    4h 49m
    $204–942

  7. Train to Ronald Reagan Washington National Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Wilmington to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Raleigh-Durham International Airport (RDU)plane plane DCA - RDU
    5h 41m
    $585–1,824

  8. Train to Newark Liberty International Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Wilmington to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)plane plane EWR - RDU
    5h 40m
    $229–1,075

  9. Train, subway to Washington Dulles International Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Wilmington to Washington Union Stationtrain train
    2. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Raleigh-Durham International Airport (RDU)plane plane IAD - RDU
    6h 22m
    $355–2,023

  10. Train to Philadelphia International Airport, fly to Piedmont Triad International Airport, train

    1. Take the train from Wilmington to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Piedmont Triad International Airport (GSO)plane plane PHL - GSO
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    5h 58m
    $175–1,370

  11. Train (Amtrak)

    1. Take the train from Wilmington to Durham Amtrak Stationtrain train Carolinian
    10h 29m
    $140–290

Wilmington to Durham by train (Amtrak)

Calendar7Weekly Trains
Duration9h 25mAverage Duration
Ticket$125Cheapest Price
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Questions & Answers

Map of how to get from Wilmington to Durham.ExpandLaunch map view
  • Distance: 387.4 mi
  • Duration: 4h 54m

What companies run services between Wilmington, DE, USA and Durham, NC, USA?

You can take a bus from Wilmington, DE - 3 W 4th St to Durham Station via Baltimore, MD, Durham, and North Pointe Dr at Woodmont Dr in around 8h 56m. Alternatively, you can take a train from Wilmington to Durham Amtrak Station via Washington Union Station in around 9h 25m.

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