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How to get fromWilmington to Florida Keysby train, plane, bus (Greyhound, Flixbus), bus, car, or shuttle

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There are 8 ways to get from Wilmington to Florida Keys by train, plane, bus (Greyhound, Flixbus), bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Philadelphia International Airport, fly to Key West International Airport

    best
    1. Take the train from Wilmington to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Key West International Airport (EYW)plane plane PHL - EYW
    8h 2m
    $206–1,189

  2. Train to Newark Liberty International Airport, fly to Key West International Airport

    cheapest
    1. Take the train from Wilmington to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Key West International Airport (EYW)plane plane EWR - EYW
    8h 54m
    $200–573

  3. Bus

    1. Take the bus from Wilmington Bus Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Miamibus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    31h 44m
    $219–379

  4. Train, bus

    1. Take the train from Wilmington to Hollywood Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    32h 52m
    $424–875

  5. Drive 1,300.7 mi

    1. Drive from Wilmington to Florida Keyscar car 1,300.7 mi
    22h 25m
    $238–343

  6. Train to Ronald Reagan Washington National Airport, fly to Key West International Airport

    1. Take the train from Wilmington to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Key West International Airport (EYW)plane plane DCA - EYW
    9h 8m
    $236–1,362

  7. Train to Philadelphia International Airport, fly to Miami International Airport, shuttle

    1. Take the train from Wilmington to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Miami International Airport (MIA)plane plane PHL - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 27m
    $301–1,129

  8. Train to Philadelphia International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the train from Wilmington to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane PHL - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 47m
    $281–1,209

Wilmington to Florida Keys by bus, taxi, and foot

Calendar8Weekly Services
Duration31h 44mAverage Duration
Ticket$219Cheapest Price
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Questions & Answers

Map of how to get from Wilmington to Florida Keys.ExpandLaunch map view
  • Distance: 1,179 mi
  • Duration: 8h 2m

What companies run services between Wilmington, DE, USA and Florida Keys, FL, USA?

You can take a bus from Wilmington Bus Station to Florida Keys via Washington Union Station, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 31h 44m.

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Bus operators

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