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How to get fromWindsor to Mayo Clinicby plane, bus (Flixbus), car, bus, train, or bus (Amtrak)

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There are 6 ways to get from Windsor to Mayo Clinic by plane, bus (Flixbus), car, bus, train, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Detroit (DTW) to Rochester (RST)plane plane DTW - RST
    7h 17m
    $99–593

  2. Bus

    1. Take the bus from Detroit Bus Station to Milwaukee Intermodal Stationbus bus FlixBus 2550
    2. Take the bus from Milwaukee to Rochesterbus bus Jefferson Lines 966
    14h 36m
    $126–191

  3. Drive  630.9 mi

    1. Drive from Windsor to Mayo Cliniccar car 630.9 mi
    10h 27m
    $130–188

  4. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Detroit (DTW) to Minneapolis–Saint Paul International Airport (MSP)plane plane DTW - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 4m
    $653–1,253

  5. Train, bus

    1. Take the train from Detroit to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    16h 21m
    $226–371

  6. Bus via Chicago

    1. Take the bus from Detroit to Chicago Union Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    16h 37m

Detroit (DTW) to Rochester (RST) flights

Calendar70Weekly Planes
Duration6h 38mAverage Duration
Ticket$95Cheapest Price
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Comparing Your Travel Options

Map of how to get from Windsor to Mayo Clinic.ExpandLaunch map view
  • Distance: 510.5 mi
  • Duration: 7h 17m

What companies run services between Windsor, ON, Canada and Mayo Clinic, MN, USA?

Delta and American Airlines fly from Detroit (DTW) to Rochester (RST) every 3 hours. Alternatively, you can take a vehicle from Windsor to Mayo Clinic via Detroit Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 14h 36m.

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