There are 8 ways to get from Winona to Des Moines by bus, car, taxi, plane, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Winona St. University to Rochesterbus
- Take the bus from Rochester to Owatonnabus
- Take the bus from Owatonna to Des Moinesbus
7h 59m$77–146Drive 245.8 mi
cheapest- Drive from Winona to Des Moinescar 245.8 mi
4h 11m$45–65Taxi to La Crosse, fly
- Take the taxi from Winona to La-Crosse-Airport-LSEtaxi
- Fly from La Crosse (LSE) to Des Moines (DSM)plane LSE - DSM
5h 15m$183–699Train, bus
- Take the train from Winona to St. Paul-Minneapolistrain Empire Builder / ...
- Take the bus from St. Paul to Des Moinesbus Jefferson Lines 805
8h 11m$92–150Bus via Saint Paul
- Take the bus from Winona St. University to St. Paulbus Jefferson Lines 966
- Take the bus from Saint Paul Union Depot to Des Moinesbus Greyhound US0156
9h$73–122Drive to Chippewa Valley Regional Airport, fly
- Drive from Winona to Eau-Claire-Airport-EAUcar
- Fly from Chippewa Valley Regional Airport (EAU) to Des Moines (DSM)plane EAU - DSM
7h 11m$140–690Train to Minneapolis–Saint Paul International Airport, fly
- Take the train from Winona to St. Paul-Minneapolistrain
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Des Moines (DSM)plane MSP - DSM
5h 25m$131–684Bus to Rochester, fly
- Take the bus from Winona St. University to Rochesterbus
- Fly from Rochester (RST) to Des Moines (DSM)plane RST - DSM
7h 51m$120–642
Winona to Des Moines by bus
Questions & Answers
The cheapest way to get from Winona to Des Moines is to drive which costs $45 - $65 and takes 4h 11m.
The fastest way to get from Winona to Des Moines is to drive which takes 4h 11m and costs $45 - $65.
No, there is no direct bus from Winona to Des Moines. However, there are services departing from Winona St. University and arriving at Des Moines via Rochester and Owatonna. The journey, including transfers, takes approximately 7h 59m.
The distance between Winona and Des Moines is 280 miles. The road distance is 247.3 miles.
The best way to get from Winona to Des Moines without a car is to bus which takes 7h 59m and costs $75 - $150.
It takes approximately 7h 59m to get from Winona to Des Moines, including transfers.
Winona to Des Moines bus services, operated by Jefferson Lines, depart from Winona St. University station.
Winona to Des Moines bus services, operated by Jefferson Lines, arrive at Rochester station.
Yes, the driving distance between Winona to Des Moines is 247 miles. It takes approximately 4h 11m to drive from Winona to Des Moines.
Book your Winona to Des Moines bus tickets online with Omio.
What companies run services between Winona, MN, USA and Des Moines, IA, USA?
You can take a bus from Winona St. University to Des Moines via Rochester and Owatonna in around 7h 59m.
- Website
- delta.com
Flights from Minneapolis–Saint Paul International Airport to Des Moines
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $85–600
Flights from Rochester to Des Moines via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $80–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Winona to St. Paul-Minneapolis
- Ave. Duration
- 2h 16m
- Frequency
- 3 times a day
- Estimated price
- $27–65
- Website
- Amtrak
Train from Winona to St. Paul-Minneapolis
- Ave. Duration
- 2h 16m
- Frequency
- 3 times a day
- Estimated price
- $27–65
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Winona St. University to Rochester
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $22–35
- Book at
- Jefferson Lines
- Adult
- $22–35
Bus from Owatonna to Des Moines
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from St. Paul to Des Moines
- Ave. Duration
- 4h 55m
- Frequency
- 4 times a week
- Estimated price
- $65–90
- Book at
- Jefferson Lines
- Adult
- $65–90
Bus from Winona St. University to St. Paul
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
Bus from Winona St. University to Rochester
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $22–35
- Book at
- Jefferson Lines
- Adult
- $22–35
- Ave. Duration
- 31 min
- Estimated price
- $65–80
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