There are 7 ways to get from Winona to Louisville by taxi, plane, train, bus, bus (Greyhound, Flixbus), car, or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to La Crosse, fly
best- Take the taxi from Winona to La-Crosse-Airport-LSEtaxi
- Fly from La Crosse (LSE) to Louisville International Airport (SDF)plane LSE - SDF
5h 54m$167–681Drive 597.8 mi
cheapest- Drive from Winona to Louisvillecar 597.8 mi
10h 2m$110–158Train, bus
- Take the train from Winona to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville Bus Stationbus
14h 28m$152–341Bus
- Take the bus from Winona St. University to Milwaukeebus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Louisville Bus Stationbus
14h 30m$119–180Drive to Chippewa Valley Regional Airport, fly
- Drive from Winona to Eau-Claire-Airport-EAUcar
- Fly from Chippewa Valley Regional Airport (EAU) to Louisville International Airport (SDF)plane EAU - SDF
7h 31m$114–672Train to Minneapolis–Saint Paul International Airport, fly
- Take the train from Winona to St. Paul-Minneapolistrain
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF)plane MSP - SDF
7h 5m$160–815Bus via Lafayette
- Take the bus from Winona St. University to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus
- Take the bus from Lafayette Amtrak Station to Louisville, KYbus
16h 31m$124–216
Winona to Louisville by train and bus
Comparing Your Travel Options
The cheapest way to get from Winona to Louisville is to drive which costs $100 - $160 and takes 10h 2m.
The fastest way to get from Winona to Louisville is to taxi and fly which takes 5h 54m and costs $160 - $700.
No, there is no direct bus from Winona to Louisville station. However, there are services departing from Winona St. University and arriving at Louisville Bus Station via Milwaukee Intermodal Station and Chicago Bus Station. The journey, including transfers, takes approximately 14h 30m.
The distance between Winona and Louisville is 524 miles. The road distance is 601.2 miles.
The best way to get from Winona to Louisville without a car is to train and bus which takes 14h 28m and costs $150 - $350.
It takes approximately 5h 54m to get from Winona to Louisville, including transfers.
Winona to Louisville bus services, operated by Jefferson Lines, depart from Winona St. University station.
Winona to Louisville bus services, operated by Jefferson Lines, arrive at Milwaukee station.
Louisville is 1h ahead of Winona. It is currently 3:13 PM in Winona and 4:13 PM in Louisville.
Yes, the driving distance between Winona to Louisville is 601 miles. It takes approximately 10h 2m to drive from Winona to Louisville.
What companies run services between Winona, MN, USA and Louisville, KY, USA?
You can take a bus from Winona St. University to Louisville Bus Station via Milwaukee, Milwaukee Intermodal Station, and Chicago Bus Station in around 14h 30m.
- Website
- delta.com
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $130–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Winona to Chicago Union Station
- Ave. Duration
- 5h 44m
- Frequency
- 3 times a day
- Estimated price
- $80–180
- Website
- Amtrak
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $50–120
- Website
- Amtrak
Train from Winona to St. Paul-Minneapolis
- Ave. Duration
- 2h 16m
- Frequency
- 3 times a day
- Estimated price
- $26–60
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a day
- Estimated price
- $18–29
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- $13–22
- Website
- Greyhound
Bus from Chicago Bus Station to Louisville Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- 4 times a day
- Estimated price
- $45–75
- Website
- Greyhound
- Ave. Duration
- 31 min
- Estimated price
- $65–80
Want to know more about travelling around United States
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Booking & Getting There
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