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How to get fromWinona to Louisvilleby taxi, plane, train, bus, bus (Flixbus, Amtrak), car, or bus (Amtrak)

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There are 8 ways to get from Winona to Louisville by taxi, plane, train, bus, bus (Flixbus, Amtrak), car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to La Crosse, fly

    best
    1. Take the taxi from Winona to La-Crosse-Airport-LSEtaxi taxi
    2. Fly from La Crosse (LSE) to Louisville International Airport (SDF)plane plane LSE - SDF
    5h 32m
    $167–731

  2. Drive  597.8 mi

    cheapest
    1. Drive from Winona to Louisvillecar car 597.8 mi
    10h 2m
    $103–148

  3. Train, bus (Amtrak)

    1. Take the train from Winona to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 33m
    $291–474

  4. Bus via Lafayette

    1. Take the bus from Winona St. University to Madisonbus bus
    2. Take the bus from Madison to Lafayette Bus Stopbus bus
    3. Take the bus from Lafayette Amtrak Station to Louisville, KYbus bus
    15h 35m
    $115–176

  5. Drive to Chippewa Valley Regional Airport, fly

    1. Drive from Winona to Eau-Claire-Airport-EAUcar car
    2. Fly from Chippewa Valley Regional Airport (EAU) to Louisville International Airport (SDF)plane plane EAU - SDF
    8h 11m
    $123–671

  6. Train to Minneapolis–Saint Paul International Airport, fly

    1. Take the train from Winona to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF)plane plane MSP - SDF
    7h 10m
    $199–892

  7. Bus to Rochester, fly

    1. Take the bus from Winona St. University to Rochesterbus bus
    2. Fly from Rochester (RST) to Louisville International Airport (SDF)plane plane RST - SDF
    8h 37m
    $134–724

  8. Bus

    1. Take the bus from Winona St. University to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Louisville, KYbus bus
    15h 41m
    $121–181

Winona to Louisville by train and bus (Amtrak)

Calendar3Weekly Services
Duration14h 33mAverage Duration
Ticket$291Cheapest Price
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Comparing Your Travel Options

Map of how to get from Winona to Louisville.ExpandLaunch map view
  • Distance: 520.8 mi
  • Duration: 5h 32m

What companies run services between Winona, MN, USA and Louisville, KY, USA?

You can take a bus from Winona St. University to Louisville, KY via Madison, Lafayette Bus Stop, and Lafayette Amtrak Station in around 15h 35m.

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