There are 6 ways to get from Winston-Salem, NC to Charleston by train (Amtrak), bus, train, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from High Point to Selma Stationtrain Carolinian
- Take the train from Selma Station to Charleston Amtrak Stationtrain Palmetto
8h 37m$180–328Drive 282 mi
cheapest- Drive from Winston-Salem, NC to Charlestoncar 282 mi
4h 50m$52–75Bus, train
- Take the bus from Winston-Salem to Fayettevillebus Winston-Salem to Fayetteville
- Take the train from Fayetteville Amtrak Station to Charleston Amtrak Stationtrain Silver Meteor / ...
9h 45m$89–180Fly from Piedmont Triad International Airport
- Fly from Piedmont Triad International Airport (GSO) to Charleston International Airport (CHS)plane GSO - CHS
5h 14m$370–1,370Bus (Greyhound)
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus Greyhound US0670 / ...
- Take the bus from Charlotte Bus Station to Charleston Bus Stationbus Greyhound US0643S
10h 28m$64–122Bus to Charlotte Douglas International Airport, fly
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Charleston International Airport (CHS)plane CLT - CHS
5h 53m$76–421
Piedmont Triad International Airport (GSO) to Charleston International Airport (CHS) flights
Questions & Answers
The cheapest way to get from Winston-Salem, NC to Charleston is to drive which costs $50 - $75 and takes 4h 50m.
The fastest way to get from Winston-Salem, NC to Charleston is to drive which takes 4h 50m and costs $50 - $75.
No, there is no direct bus from Winston-Salem, NC to Charleston. However, there are services departing from Winston Salem(Trans Center) and arriving at Transit Mall via Charlotte Bus Station, North Charleston Transit Center and Rivers Ave / Cosgrove Ave. The journey, including transfers, takes approximately 10h 28m.
No, there is no direct train from Winston-Salem, NC to Charleston station. However, there are services departing from High Point and arriving at Charleston Amtrak Station via Selma Station. The journey, including transfers, takes approximately 8h 37m.
The distance between Winston-Salem, NC and Charleston is 379 miles. The road distance is 283.7 miles.
The best way to get from Winston-Salem, NC to Charleston without a car is to train which takes 8h 37m and costs $180 - $330.
It takes approximately 8h 37m to get from Winston-Salem, NC to Charleston, including transfers.
Winston-Salem, NC to Charleston bus services, operated by Greyhound USA, depart from Winston Salem(Trans Center) station.
Winston-Salem, NC to Charleston train services, operated by Amtrak, depart from High Point station.
The best way to get from Winston-Salem, NC to Charleston is to train which takes 8h 37m and costs $180 - $330. Alternatively, you can fly, which costs $370 - $1,400 and takes 5h 14m, you could also bus, which costs $60 - $130 and takes 10h 28m.
What companies run services between Winston-Salem, NC, USA and Charleston, SC, USA?
You can take a vehicle from Winston-Salem, NC to Charleston via High Point, Selma Station, and Charleston Amtrak Station in around 8h 37m. Alternatively, American Airlines, Delta, and United Airlines fly from Piedmont Triad International Airport (GSO) to Charleston International Airport (CHS) hourly.
- Website
- aa.com
Flights from Piedmont Triad International Airport to Charleston International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $60–420
Flights from Piedmont Triad International Airport to Charleston International Airport via Philadelphia
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $120–650
Flights from Charlotte Douglas International Airport to Charleston International Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- $50–380
- Website
- delta.com
Flights from Piedmont Triad International Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $90–550
Flights from Piedmont Triad International Airport to Charleston International Airport via Detroit
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $140–700
- Website
- united.com
Flights from Piedmont Triad International Airport to Charleston International Airport via Washington Dulles
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from High Point to Selma Station
- Ave. Duration
- 2h 44m
- Frequency
- Once daily
- Estimated price
- $35–85
- Website
- Amtrak
Train from Selma Station to Charleston Amtrak Station
- Ave. Duration
- 4h 18m
- Frequency
- Once daily
- Estimated price
- $70–150
- Website
- Amtrak
Train from Fayetteville Amtrak Station to Charleston Amtrak Station
- Ave. Duration
- 3h 21m
- Frequency
- Twice daily
- Estimated price
- $55–120
- Website
- Amtrak
- Phone
- +1 704-348-1200
- [email protected]
- Website
- sunwaycharters.com
Bus from Winston-Salem to Fayetteville
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $23–35
- Schedules at
- sunwaycharters.com
- Passenger
- $23–35
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Winston-Salem to Fayetteville
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $21–45
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $11–22
- Website
- Greyhound
Bus from Charlotte Bus Station to Charleston Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $11–22
- Website
- Greyhound
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More Questions & Answers
Winston-Salem, NC to Charleston bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Winston-Salem, NC to Charleston train services, operated by Amtrak, arrive at Selma Station.
Yes, the driving distance between Winston-Salem, NC to Charleston is 284 miles. It takes approximately 4h 50m to drive from Winston-Salem, NC to Charleston.
There are 1639+ hotels available in Charleston.







