There are 7 ways to get from Winston-Salem to Biloxi by plane, bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Piedmont Triad International Airport to Gulfport-Biloxi Regional Airport
best- Fly from Piedmont Triad International Airport (GSO) to Gulfport-Biloxi Regional Airport (GPT)plane GSO - GPT
5h 52m$124–458Fly Piedmont Triad International Airport to Mobile Regional Airport, bus
cheapest- Fly from Piedmont Triad International Airport (GSO) to Mobile Regional Airport (MOB)plane GSO - MOB
- Take the bus from Mobile Bus Station to Biloxi Transit Centerbus
8h 2m$116–448Bus
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Atlanta Downtownbus
- Take the bus from Atlanta to Biloxibus
14h 17m$137–194Drive 690.5 mi
- Drive from Winston-Salem to Biloxicar 690.5 mi
12h 1m$118–171Bus to Charlotte Douglas International Airport, fly to Gulfport-Biloxi Regional Airport
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Gulfport-Biloxi Regional Airport (GPT)plane CLT - GPT
5h 34m$118–462Bus via LaGrange
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to La Grange Bus Stationbus
- Take the bus from La Grange Bus Station to Biloxibus
14h 26m$135–209Bus #2 (Greyhound)
- Take the bus from Winston Salem(Trans Center) to Atlanta Bus Stationbus Greyhound US0670
- Take the bus from Atlanta Bus Station to Biloxi Transit Centerbus Greyhound US0602
16h 50m$136–210
Winston-Salem to Biloxi by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Winston-Salem to Biloxi is to drive which costs $110 - $170 and takes 12h 1m.
The fastest way to get from Winston-Salem to Biloxi is to bus and fly which takes 5h 34m and costs $110 - $470.
No, there is no direct bus from Winston-Salem to Biloxi. However, there are services departing from Winston Salem(Trans Center) and arriving at Biloxi via Charlotte Bus Station and Atlanta. The journey, including transfers, takes approximately 14h 17m.
The distance between Winston-Salem and Biloxi is 699 miles. The road distance is 694.5 miles.
The best way to get from Winston-Salem to Biloxi without a car is to bus which takes 14h 17m and costs $130 - $200.
It takes approximately 5h 52m to get from Winston-Salem to Biloxi, including transfers.
Winston-Salem to Biloxi bus services, operated by Greyhound USA, depart from Winston Salem(Trans Center) station.
The best way to get from Winston-Salem to Biloxi is to fly which takes 5h 52m and costs $120 - $460. Alternatively, you can bus, which costs $130 - $200 and takes 14h 17m.
Winston-Salem to Biloxi bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Biloxi is 1h behind Winston-Salem. It is currently 9:06 PM in Winston-Salem and 8:06 PM in Biloxi.
What companies run services between Winston-Salem, NC, USA and Biloxi, MS, USA?
Delta and American Airlines fly from Piedmont Triad International Airport (GSO) to Gulfport-Biloxi Regional Airport (GPT) every 4 hours. Alternatively, you can take a bus from Winston Salem(Trans Center) to Biloxi via Charlotte Bus Station, Atlanta Downtown, Civic Center Station, Doraville Station, and Atlanta in around 14h 17m.
- Website
- delta.com
Flights from Piedmont Triad International Airport to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $70–390
Flights from Charlotte Douglas International Airport to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $65–390
Flights from Piedmont Triad International Airport to Mobile Regional Airport via Atlanta
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $65–380
- Website
- aa.com
Flights from Piedmont Triad International Airport to Gulfport-Biloxi Regional Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $70–390
Flights from Piedmont Triad International Airport to Gulfport-Biloxi Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h
- When
- Every day
- Estimated price
- $120–550
Flights from Charlotte Douglas International Airport to Gulfport-Biloxi Regional Airport
- Ave. Duration
- 2h 8m
- When
- Every day
- Estimated price
- $65–390
Flights from Piedmont Triad International Airport to Mobile Regional Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $65–380
Flights from Piedmont Triad International Airport to Mobile Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 21m
- When
- Every day
- Estimated price
- $120–550
- Website
- united.com
Flights from Piedmont Triad International Airport to Mobile Regional Airport via Washington Dulles
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $95–460
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Mobile Bus Station to Biloxi Transit Center
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- $10–15
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Charlotte Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 25m
- Frequency
- Every 2 hours
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Atlanta Bus Station to La Grange Bus Station
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $11–18
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Atlanta Bus Station
- Ave. Duration
- 6h 55m
- Frequency
- Every 4 hours
- Estimated price
- $60–90
- Website
- Greyhound
Bus from Atlanta Bus Station to Biloxi Transit Center
- Ave. Duration
- 8h 55m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Charlotte Bus Station to Atlanta Downtown
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from Mobile Bus Station to Biloxi Transit Center
- Ave. Duration
- 55 min
- Frequency
- Twice daily
- Estimated price
- $8–13
- Schedules at
- Flixbus USA
Bus from Charlotte Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- Every 4 hours
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Atlanta to Biloxi
- Ave. Duration
- 6h 2m
- Frequency
- Once daily
- Estimated price
- $85–110
- Schedules at
- Omnibus Express
Bus from La Grange Bus Station to Biloxi
- Ave. Duration
- 4h 58m
- Frequency
- Once daily
- Estimated price
- $75–100
- Schedules at
- Omnibus Express
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Booking & Getting There
Yes, the driving distance between Winston-Salem to Biloxi is 695 miles. It takes approximately 12h 1m to drive from Winston-Salem to Biloxi.
Book your Winston-Salem to Biloxi bus tickets online with Omio.
There are 388+ hotels available in Biloxi.





