There are 10 ways to get from Winston-Salem to Boston by bus, plane, train, bus (Flixbus), car, bus (Greyhound), or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Charlotte Douglas International Airport, fly to Theodore Francis Green State Airport, train
best- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Theodore Francis Green State Airport (PVD)plane CLT - PVD
- Take the train from TF Green Airport to South Stationtrain
7h 47m$86–372Bus to Raleigh-Durham International Airport, fly to Theodore Francis Green State Airport, train
cheapest- Take the bus from Winston Salem(Trans Center) to Durhambus
- Fly from Raleigh-Durham International Airport (RDU) to Theodore Francis Green State Airport (PVD)plane RDU - PVD
- Take the train from TF Green Airport to South Stationtrain
8h 37m$77–343Bus via New York
- Take the bus from Winston-Salem, NC to New York, NYbus Winston-Salem
- Take the bus from NYC Downtown to Bostonbus FlixBus 2611
17h 20m$111–159Bus, train
- Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus
- Take the train from Greensboro to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
17h 21m$405–637Drive 738.3 mi
- Drive from Winston-Salem to Bostoncar 738.3 mi
14h 13m$135–195Bus to Charlotte Douglas International Airport, fly to Manchester Airport, bus
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Manchester Airport (MHT)plane CLT - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
7h 57m$106–480Fly Piedmont Triad International Airport to Laguardia Airport, train
- Fly from Piedmont Triad International Airport (GSO) to Laguardia Airport (LGA)plane GSO - LGA
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
8h 35m$242–878Bus to Charlotte Douglas International Airport, fly to Bradley International Airport, bus
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Bradley International Airport (BDL)plane CLT - BDL
- Take the bus from Hartford Union Station to Bostonbus
8h 38m$134–655Bus
- Take the bus from Winston Salem(Trans Center) to Port Authority Bus Terminalbus Greyhound US0670
- Take the bus from New York to Bostonbus Ppb 5623 / ...
19h 37m$153–241Train (Amtrak)
- Take the train from High Point to Lynchburgtrain Crescent
- Take the train from Lynchburg to Bostontrain Northeast Regional
21h 44m$413–665
Winston-Salem to Boston by bus and train
Comparing Your Travel Options
The cheapest way to get from Winston-Salem to Boston is to bus via New York which costs $110 - $160 and takes 17h 20m.
The fastest way to get from Winston-Salem to Boston is to bus and fly and train which takes 7h 47m and costs $85 - $380.
No, there is no direct bus from Winston-Salem to Boston. However, there are services departing from Winston-Salem, NC and arriving at Boston via NYC Downtown. The journey, including transfers, takes approximately 17h 20m.
No, there is no direct train from Winston-Salem to Boston. However, there are services departing from High Point and arriving at Boston via Lynchburg. The journey, including transfers, takes approximately 21h 44m.
The distance between Winston-Salem and Boston is 825 miles. The road distance is 742.6 miles.
The best way to get from Winston-Salem to Boston without a car is to bus via New York which takes 17h 20m and costs $110 - $160.
It takes approximately 7h 47m to get from Winston-Salem to Boston, including transfers.
Winston-Salem to Boston bus services, operated by Wanda Coach, depart from Winston-Salem, NC station.
Winston-Salem to Boston train services, operated by Amtrak, depart from High Point station.
The best way to get from Winston-Salem to Boston is to bus via New York which takes 17h 20m and costs $110 - $160. Alternatively, you can train, which costs $410 - $700 and takes 21h 44m.
What companies run services between Winston-Salem, NC, USA and Boston, MA, USA?
You can take a bus from Winston-Salem, NC to Boston via New York, NY and NYC Downtown in around 17h 20m. Alternatively, you can take a bus from Winston-Salem Transportation Center to Boston via High Point Terminal, High Point, and Lynchburg in around 21h 44m.
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Theodore Francis Green State Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $60–330
Flights from Charlotte Douglas International Airport to Manchester Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- $80–440
Flights from Charlotte Douglas International Airport to Manchester Airport via Philadelphia
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $80–440
Flights from Charlotte Douglas International Airport to Manchester Airport via Reagan Washington
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $80–440
Flights from Raleigh-Durham International Airport to Theodore Francis Green State Airport via Philadelphia
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $50–300
Flights from Raleigh-Durham International Airport to Theodore Francis Green State Airport via Reagan Washington
- Ave. Duration
- 4h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $50–300
Flights from Piedmont Triad International Airport to Laguardia Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $100–650
Flights from Piedmont Triad International Airport to Laguardia Airport via Reagan Washington
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $100–650
Flights from Piedmont Triad International Airport to Laguardia Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $120–700
Flights from Charlotte Douglas International Airport to Bradley International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $100–600
- Website
- southwest.com
Flights from Charlotte Douglas International Airport to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $60–330
Flights from Charlotte Douglas International Airport to Manchester Airport via Baltimore
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $80–440
Flights from Raleigh-Durham International Airport to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 3h 36m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $50–300
Flights from Charlotte Douglas International Airport to Bradley International Airport via Baltimore
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $100–600
- Website
- united.com
Flights from Charlotte Douglas International Airport to Manchester Airport via Washington Dulles
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $80–440
Flights from Raleigh-Durham International Airport to Theodore Francis Green State Airport via Washington Dulles
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $50–310
Flights from Piedmont Triad International Airport to Laguardia Airport via Washington Dulles
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $100–650
- Website
- delta.com
Flights from Piedmont Triad International Airport to Laguardia Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $100–650
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Theodore Francis Green State Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $110–700
Train from TF Green Airport to South Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from TF Green Airport to South Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Greensboro to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 11h 13m
- Frequency
- Twice daily
- Estimated price
- $280–430
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from High Point to Lynchburg
- Ave. Duration
- 2h 36m
- Frequency
- Once daily
- Estimated price
- $70–110
- Website
- Amtrak
Train from Lynchburg to Boston
- Ave. Duration
- 16h 25m
- Frequency
- Twice daily
- Estimated price
- $340–550
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 47m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 47m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $13–20
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Greensboro Bus Stop
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- $4–8
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $13–20
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Durham
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $13–20
- Website
- Greyhound
Bus from Hartford Union Station to Boston
- Ave. Duration
- 1h 45m
- Frequency
- Every 2 hours
- Estimated price
- $17–27
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Port Authority Bus Terminal
- Ave. Duration
- 14h 10m
- Frequency
- Twice daily
- Estimated price
- $110–170
- Website
- Greyhound
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Winston-Salem, NC to New York, NY
- Ave. Duration
- 11h 15m
- Frequency
- 3 times a day
- Estimated price
- $80–110
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $80–110
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from NYC Downtown to Boston
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from Hartford Union Station to Boston
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $15–23
- Schedules at
- Flixbus USA
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from New York to Boston
- Ave. Duration
- 4h 35m
- Frequency
- Hourly
- Estimated price
- $40–75
- Website
- Peter Pan
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Winston-Salem to Boston bus services, operated by Wanda Coach, arrive at New York, NY station.
Winston-Salem to Boston train services, operated by Amtrak, arrive at Lynchburg station.
Yes, the driving distance between Winston-Salem to Boston is 743 miles. It takes approximately 14h 13m to drive from Winston-Salem to Boston.
Book your Winston-Salem to Boston train tickets online with Omio.
Book your Winston-Salem to Boston bus tickets online with Omio.
There are 1640+ hotels available in Boston.


















