Rome2Rio

How to get fromWinston-Salem to Buffaloby plane, bus, car, or bus (Greyhound, Flixbus)

Find Transport to Buffalo

See all options

There are 7 ways to get from Winston-Salem to Buffalo by plane, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Piedmont Triad International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Buffalo Niagara International Airport (BUF)plane plane GSO - BUF
    6h 21m
    $160–852

  2. Bus

    cheapest
    1. Take the bus from Winston Salem(Trans Center) to Charleston, WVbus bus
    2. Take the bus from Charleston, WV to Robert K Pfaff Transit Center - Akronbus bus
    3. Take the bus from Robert K Pfaff Transit Center - Akron to Buffalo, NYbus bus
    15h 20m
    $66–189

  3. Drive 600.3 mi

    1. Drive from Winston-Salem to Buffalocar car 600.3 mi
    10h 27m
    $110–159

  4. Bus to Charlotte Douglas International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF)plane plane CLT - BUF
    5h 51m
    $149–808

  5. Bus to Raleigh-Durham International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Buffalo Niagara International Airport (BUF)plane plane RDU - BUF
    6h 54m
    $139–510

  6. Bus to Charlotte Douglas International Airport, fly to Rochester, bus

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Rochester (ROC)plane plane CLT - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 32m
    $176–824

  7. Bus via Washington

    1. Take the bus from Winston Salem(Trans Center) to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Pittsburgh Intermodal Stationbus bus
    3. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    23h 45m
    $140–376

Winston-Salem to Buffalo by bus

Calendar7Weekly Buses
Duration15h 20mAverage Duration
Ticket$66Cheapest Price
See schedules

Questions & Answers

Map of how to get from Winston-Salem to Buffalo.ExpandLaunch map view
  • Distance: 513.8 mi
  • Duration: 6h 21m

What companies run services between Winston-Salem, NC, USA and Buffalo, NY, USA?

United Airlines, Delta, and American Airlines fly from Piedmont Triad International Airport (GSO) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Winston Salem(Trans Center) to Buffalo, NY via Charleston, WV and Robert K Pfaff Transit Center - Akron in around 15h 20m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers