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How to get fromWinston-Salem to Buffaloby plane, bus, car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Winston-Salem to Buffalo by plane, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Piedmont Triad International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Buffalo Niagara International Airport (BUF)plane plane GSO - BUF
    6h 39m
    $130–726

  2. Bus

    cheapest
    1. Take the bus from Winston Salem(Trans Center) to Charleston, WVbus bus
    2. Take the bus from Charleston, WV to Robert K Pfaff Transit Center - Akronbus bus
    3. Take the bus from Robert K Pfaff Transit Center - Akron to Buffalo, NYbus bus
    15h 20m
    $66–189

  3. Drive 600.3 mi

    1. Drive from Winston-Salem to Buffalocar car 600.3 mi
    10h 27m
    $110–159

  4. Bus to Charlotte Douglas International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF)plane plane CLT - BUF
    6h 20m
    $115–676

  5. Bus to Raleigh-Durham International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Buffalo Niagara International Airport (BUF)plane plane RDU - BUF
    7h 13m
    $136–450

  6. Bus to Charlotte Douglas International Airport, fly to Rochester, bus

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Rochester (ROC)plane plane CLT - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 49m
    $182–865

  7. Bus via Washington

    1. Take the bus from Winston Salem(Trans Center) to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    23h 45m
    $145–257

Winston-Salem to Buffalo by bus

Calendar7Weekly Buses
Duration15h 20mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

Map of how to get from Winston-Salem to Buffalo.ExpandLaunch map view
  • Distance: 509.5 mi
  • Duration: 6h 39m

What companies run services between Winston-Salem, NC, USA and Buffalo, NY, USA?

Delta, United Airlines, and American Airlines fly from Piedmont Triad International Airport (GSO) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Winston Salem(Trans Center) to Buffalo, NY via Charleston, WV and Robert K Pfaff Transit Center - Akron in around 15h 20m.

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