There are 7 ways to get from Winston-Salem to Carlisle by bus, plane, bus (Greyhound), train, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Charlotte Douglas International Airport, fly to Harrisburg International Airport, bus
best- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Harrisburg International Airport (MDT)plane CLT - MDT
- Take the bus from Market Square Transfer Center to Hanover St & High Stbus
7h 17m$82–452Drive 373 mi
cheapest- Drive from Winston-Salem to Carlislecar 373 mi
6h 47m$69–99Bus (Greyhound)
- Take the bus from Winston Salem(Trans Center) to Baltimore Downtown Bus Stationbus Greyhound US0670
- Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus Greyhound US0430
14h 1m$72–137Train, bus
- Take the train from High Point to Washington Union Stationtrain Crescent / ...
- Take the bus from Washington Union Station to Harrisburg Bus Stationbus Greyhound US0430
14h 30m$110–241Fly Piedmont Triad International Airport to Philadelphia International Airport, train
- Fly from Piedmont Triad International Airport (GSO) to Philadelphia International Airport (PHL)plane GSO - PHL
- Take the train from 30th Street Station to Harrisburgtrain
8h 33m$142–698Bus, train
- Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus
- Take the train from Greensboro to 30th Street Stationtrain
- Take the train from 30th Street Station to Harrisburgtrain
15h 33m$165–360Bus via Fredericksburg
- Take the bus from Greensboro Bus Stop to Fredericksburgbus
- Take the bus from Fredericksburg to Washington Union Stationbus
- Take the bus from Washington Union Station to Harrisburg Bus Stationbus
18h 20m$82–146
Winston-Salem to Carlisle by bus and foot (Greyhound)
Questions & Answers
The cheapest way to get from Winston-Salem to Carlisle is to drive which costs $65 - $100 and takes 6h 47m.
The fastest way to get from Winston-Salem to Carlisle is to drive which takes 6h 47m and costs $65 - $100.
No, there is no direct bus from Winston-Salem to Carlisle. However, there are services departing from Winston Salem(Trans Center) and arriving at Hanover St & High St via Baltimore Downtown Bus Station and Market Square Transfer Center. The journey, including transfers, takes approximately 14h 1m.
The distance between Winston-Salem and Carlisle is 532 miles. The road distance is 375.2 miles.
The best way to get from Winston-Salem to Carlisle without a car is to bus which takes 14h 1m and costs $70 - $140.
It takes approximately 7h 17m to get from Winston-Salem to Carlisle, including transfers.
Winston-Salem to Carlisle bus services, operated by Greyhound USA, depart from Winston Salem(Trans Center) station.
Winston-Salem to Carlisle bus services, operated by Greyhound USA, arrive at Baltimore Downtown Bus Station.
Yes, the driving distance between Winston-Salem to Carlisle is 375 miles. It takes approximately 6h 47m to drive from Winston-Salem to Carlisle.
There are 60+ hotels available in Carlisle.
What companies run services between Winston-Salem, NC, USA and Carlisle, PA, USA?
You can take a bus from Winston Salem(Trans Center) to Hanover St & High St via Baltimore Downtown Bus Station, Harrisburg Bus Station, and Market Square Transfer Center in around 14h 1m.
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Harrisburg International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $65–420
Flights from Charlotte Douglas International Airport to Harrisburg International Airport via Philadelphia International Airport
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $75–450
Flights from Piedmont Triad International Airport to Philadelphia International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $90–600
Flights from Piedmont Triad International Airport to Philadelphia International Airport via Reagan Washington
- Ave. Duration
- 3h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–600
Flights from Piedmont Triad International Airport to Philadelphia International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $100–650
- Website
- united.com
Flights from Charlotte Douglas International Airport to Harrisburg International Airport via Washington Dulles
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $65–420
Flights from Piedmont Triad International Airport to Philadelphia International Airport via Washington Dulles
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $90–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from High Point to Washington Union Station
- Ave. Duration
- 6h 46m
- Frequency
- Twice daily
- Estimated price
- $90–200
- Website
- Amtrak
Train from 30th Street Station to Harrisburg
- Ave. Duration
- 1h 51m
- Frequency
- Every 2 hours
- Estimated price
- $30–70
- Website
- Amtrak
Train from Greensboro to 30th Street Station
- Ave. Duration
- 9h 13m
- Frequency
- Twice daily
- Estimated price
- $130–280
- Website
- Amtrak
Train from 30th Street Station to Harrisburg
- Ave. Duration
- 1h 51m
- Frequency
- Every 2 hours
- Estimated price
- $30–70
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $11–22
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Baltimore Downtown Bus Station
- Ave. Duration
- 9h 25m
- Frequency
- Twice daily
- Estimated price
- $60–120
- Website
- Greyhound
Bus from Baltimore Downtown Bus Station to Harrisburg Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $11–22
- Website
- Greyhound
Bus from Washington Union Station to Harrisburg Bus Station
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Greensboro Bus Stop
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- $4–8
- Website
- Greyhound
Bus from Washington Union Station to Harrisburg Bus Station
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- Greyhound
- Phone
- +1 800-632-9063
- Website
- Rabbit Transit
Bus from Market Square Transfer Center to Hanover St & High St
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $1–2
- Website
- Rabbit Transit
- Adult
- $1–2
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Greensboro Bus Stop to Fredericksburg
- Ave. Duration
- 7h 45m
- Frequency
- 4 times a week
- Estimated price
- $50–90
- Schedules at
- Flixbus USA
Bus from Fredericksburg to Washington Union Station
- Ave. Duration
- 1h
- Frequency
- 5 times a day
- Estimated price
- $8–14
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide








