Rome2Rio

How to get fromWinston-Salem to Charlestonby bus, train, car, plane, or bus (Greyhound)

Find Transport to Charleston

See all options

There are 8 ways to get from Winston-Salem to Charleston by bus, train, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Selma Stationtrain train
    3. Take the train from Selma Station to Charleston Amtrak Stationtrain train
    9h 33m
    $139–273

  2. Drive 283 mi

    cheapest
    1. Drive from Winston-Salem to Charlestoncar car 283 mi
    4h 53m
    $52–75

  3. Bus, train via Fayetteville

    1. Take the bus from Winston Salem(Trans Center) to Fayetteville Bus Stationbus bus Greyhound US0647S
    2. Take the train from Fayetteville Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    10h 20m
    $83–157

  4. Fly Piedmont Triad International Airport to Charleston International Airport

    1. Fly from Piedmont Triad International Airport (GSO) to Charleston International Airport (CHS)plane plane GSO - CHS
    6h 23m
    $330–1,324

  5. Bus, train via Fayetteville #2

    1. Take the bus from Winston Salem(Trans Center) to Raleigh Bus Stationbus bus
    2. Take the bus from Raleigh Bus Station to Fayetteville Bus Stationbus bus
    3. Take the train from Fayetteville Amtrak Station to Charleston Amtrak Stationtrain train
    10h 20m
    $84–173

  6. Bus (Greyhound)

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Charlotte Bus Station to Charleston Bus Stationbus bus Greyhound US0643S
    10h 24m
    $56–111

  7. Bus to Charlotte Douglas International Airport, fly to Charleston International Airport

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Charleston International Airport (CHS)plane plane CLT - CHS
    5h 49m
    $68–390

  8. Bus to Charlotte Douglas International Airport, fly to Hilton Head Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Hilton Head Airport (HHH)plane plane CLT - HHH
    3. Drive from Hilton Head Airport (HHH) to Charlestoncar car
    6h 39m
    $84–415

Winston-Salem to Charleston by bus and train

Calendar14Weekly Services
Duration10h 20mAverage Duration
Ticket$83Cheapest Price
See schedules

Questions & Answers

Map of how to get from Winston-Salem to Charleston.ExpandLaunch map view
  • Distance: 371.5 mi
  • Duration: 9h 33m

What companies run services between Winston-Salem, NC, USA and Charleston, SC, USA?

American Airlines, Delta, and United Airlines fly from Piedmont Triad International Airport (GSO) to Charleston International Airport (CHS) hourly. Alternatively, you can take a bus from Winston Salem(Trans Center) to Transit Mall via Charlotte Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 10h 24m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers