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How to get fromWinston-Salem to Great Smoky Mountainsby bus, car, or plane

Find Transport to Great Smoky Mountains

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There are 5 ways to get from Winston-Salem to Great Smoky Mountains by bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive (Greyhound)

    best
    1. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus Greyhound US0654s
    2. Drive from Asheville, NC to Great Smoky Mountainscar car
    4h 33m
    $35–61

  2. Drive 217.4 mi

    1. Drive from Winston-Salem to Great Smoky Mountainscar car 217.4 mi
    4h 23m
    $40–58

  3. Bus, fly to Asheville Regional Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Asheville Regional Airport (AVL)plane plane CLT - AVL
    3. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    6h 8m
    $70–380

  4. Bus, drive via Emma (Greyhound)

    1. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus Greyhound US0654s
    2. Drive from New Leicester Hwy at Walgreens to Great Smoky Mountainscar car
    5h 52m
    $36–61

  5. Bus, fly to Mcghee Tyson Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Mcghee Tyson Airport (TYS)plane plane CLT - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    6h 16m
    $111–694

Charlotte Douglas International Airport (CLT) to Asheville Regional Airport (AVL) flights

Calendar42Weekly Planes
Duration1h 2mAverage Duration
Ticket$42Cheapest Price
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Questions & Answers

Map of how to get from Winston-Salem to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 219.4 mi
  • Duration: 4h 33m

What companies run services between Winston-Salem, NC, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Winston-Salem to Great Smoky Mountains. However, you can take the bus to Asheville, NC then drive to Great Smoky Mountains. Alternatively, you can drive from Winston-Salem to Great Smoky Mountains in around 4h 23m.

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