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How to get fromWinston-Salem to Hartsvilleby bus, taxi, car, plane, bus (Greyhound, Flixbus), train, or bus (Greyhound)

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There are 6 ways to get from Winston-Salem to Hartsville by bus, taxi, car, plane, bus (Greyhound, Flixbus), train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi (Greyhound)

    best
    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the taxi from Camden to Hartsvilletaxi taxi
    4h 42m
    $143–195

  2. Drive 133.4 mi

    cheapest
    1. Drive from Winston-Salem to Hartsvillecar car 133.4 mi
    3h 16m
    $25–36

  3. Bus, fly, taxi

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Florence Regional Airport (FLO)plane plane CLT - FLO
    3. Take the taxi from Florence Regional Airport (FLO) to Hartsvilletaxi taxi
    4h 54m
    $136–458

  4. Bus

    1. Take the bus from Winston Salem(Trans Center) to Raleigh Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Raleigh Bus Station to Florencebus bus FlixBus N2472
    6h 13m
    $100–145

  5. Bus, train

    1. Take the bus from Winston-Salem to Fayettevillebus bus Winston-Salem to Fayetteville
    2. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train Palmetto / ...
    6h 51m
    $123–187

  6. Bus via Fayetteville

    1. Take the bus from Winston-Salem to Fayettevillebus bus Winston-Salem to Fayetteville
    2. Take the bus from Fayetteville, NC to Florence, SCbus bus Nyc
    8h 9m
    $117–167

Charlotte Douglas International Airport (CLT) to Florence Regional Airport (FLO) flights

Calendar14Weekly Planes
Duration1h 5mAverage Duration
Ticket$42Cheapest Price
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Questions & Answers

Map of how to get from Winston-Salem to Hartsville.ExpandLaunch map view
  • Distance: 193.5 mi
  • Duration: 4h 42m

What companies run services between Winston-Salem, NC, USA and Hartsville, SC, USA?

You can take a bus from Winston Salem(Trans Center) to Hartsville via Raleigh Bus Station and Florence in around 6h 13m.

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