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How to get fromWinston-Salem to Indianapolisby plane, bus, train, bus (Greyhound), or car

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There are 7 ways to get from Winston-Salem to Indianapolis by plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Piedmont Triad International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Indianapolis (IND)plane plane GSO - IND
    6h 20m
    $140–724

  2. Bus

    cheapest
    1. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus Charlotte
    2. Take the bus from Columbus to Indianapolis Union Stationbus bus Greyhound US0421
    14h 30m
    $89–156

  3. Bus, train

    1. Take the bus from Winston Salem(Trans Center) to Ashlandbus bus Charlotte
    2. Take the train from Ashland Amtrak Station to Indianapolistrain train Cardinal
    14h 16m
    $112–249

  4. Drive 511.4 mi

    1. Drive from Winston-Salem to Indianapoliscar car 511.4 mi
    9h 6m
    $94–135

  5. Bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Indianapolis (IND)plane plane CLT - IND
    5h 53m
    $135–647

  6. Bus to Raleigh-Durham International Airport, fly

    1. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Indianapolis (IND)plane plane RDU - IND
    7h 20m
    $130–599

  7. Bus via Winston Salem

    1. Take the bus from Winston Salem to Columbusbus bus Bsb 33
    2. Take the bus from Columbus to Indianapolisbus bus FlixBus 2511 / ...
    15h 14m
    $162–234

Winston-Salem to Indianapolis by bus and train

Calendar3Weekly Services
Duration14h 16mAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

Map of how to get from Winston-Salem to Indianapolis.ExpandLaunch map view
  • Distance: 465.3 mi
  • Duration: 6h 20m

What companies run services between Winston-Salem, NC, USA and Indianapolis, IN, USA?

Delta, American Airlines, and United Airlines fly from Piedmont Triad International Airport (GSO) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Winston Salem(Trans Center) to Indianapolis Union Station via Columbus in around 14h 30m.

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