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How to get fromWinston-Salem to Iowaby bus, plane, bus (Greyhound), train, car, or bus (Flixbus, Greyhound)

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There are 11 ways to get from Winston-Salem to Iowa by bus, plane, bus (Greyhound), train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Charlotte Douglas International Airport, fly to The Eastern Iowa Airport

    best
    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to The Eastern Iowa Airport (CID)plane plane CLT - CID
    5h 47m
    $131–505
  2. Bus to Charlotte Douglas International Airport, fly to Quad City International Airport

    cheapest
    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Quad City International Airport (MLI)plane plane CLT - MLI
    6h 58m
    $93–437
  3. Bus

    1. Take the bus from Winston Salem to Columbusbus bus
    2. Take the bus from Wilson & Ferrell Shell Station - Columbus to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    26h 30m
    $152–267
  4. Bus, train

    1. Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Charlottesvilletrain train
    3. Take the train from Charlottesville to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    32h 23m
    $508–837
  5. Drive  976.6 mi

    1. Drive from Winston-Salem to Des Moinescar car 976.6 mi
    16h 57m
    $179–258
  6. Bus to Charlotte Douglas International Airport, fly to Des Moines

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane plane CLT - DSM
    5h 47m
    $114–488
  7. Bus to Charlotte Douglas International Airport, fly to Omaha

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Omaha (OMA)plane plane CLT - OMA
    6h 5m
    $151–655
  8. Fly Piedmont Triad International Airport to Quad City International Airport

    1. Fly from Piedmont Triad International Airport (GSO) to Quad City International Airport (MLI)plane plane GSO - MLI
    7h 36m
    $110–574
  9. Bus via Chicago

    1. Take the bus from Winston Salem to Columbusbus bus
    2. Take the bus from Columbus to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    26h 50m
    $152–275
  10. Train, bus

    1. Take the train from Greensboro to Carytrain train
    2. Take the train from Cary to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    37h 58m
    $654–1,116
  11. Bus, train via Galesburg

    1. Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    5. Take the bus from Galesburg to Des Moinesbus bus
    38h 26m
    $718–1,182

Charlotte Douglas International Airport (CLT) to The Eastern Iowa Airport (CID) flights

Calendar71Weekly Planes
Duration5h 4mAverage Duration
Ticket$79Cheapest Price
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Comparing Your Travel Options

What companies run services between Winston-Salem, NC, USA and Iowa, USA?

You can take a bus from Baptist Hospital to Des Moines via Winston Salem, Wilson & Ferrell Shell Station - Columbus, Indianapolis Union Station, and Des Moines in around 26h 30m. Alternatively, American Airlines, Delta, and United Airlines fly from Piedmont Triad International Airport (GSO) to Quad City International Airport (MLI) every 2 hours.

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Train operators
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