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How to get fromWinston-Salem to Iowaby bus, plane, train, or car

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There are 7 ways to get from Winston-Salem to Iowa by bus, plane, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Charlotte Douglas International Airport, fly to Des Moines

    best
    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane plane CLT - DSM
    5h 43m
    $203–900

  2. Bus to Charlotte Douglas International Airport, fly to Quad City International Airport

    cheapest
    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Quad City International Airport (MLI)plane plane CLT - MLI
    7h 2m
    $108–511

  3. Bus, train

    1. Take the bus from Winston Salem(Trans Center) to Ashlandbus bus
    2. Take the train from Ashland Amtrak Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    25h 16m
    $190–400

  4. Drive 976.6 mi

    1. Drive from Winston-Salem to Des Moinescar car 976.6 mi
    16h 57m
    $179–258

  5. Bus to Charlotte Douglas International Airport, fly to The Eastern Iowa Airport

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to The Eastern Iowa Airport (CID)plane plane CLT - CID
    5h 42m
    $151–579

  6. Bus to Charlotte Douglas International Airport, fly to Omaha

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Omaha (OMA)plane plane CLT - OMA
    5h 59m
    $181–759

  7. Fly Piedmont Triad International Airport to Quad City International Airport

    1. Fly from Piedmont Triad International Airport (GSO) to Quad City International Airport (MLI)plane plane GSO - MLI
    7h 26m
    $120–574

Charlotte Douglas International Airport (CLT) to Des Moines (DSM) flights

Calendar82Weekly Planes
Duration4h 6mAverage Duration
Ticket$171Cheapest Price
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Questions & Answers

Map of how to get from Winston-Salem to Iowa.ExpandLaunch map view
  • Distance: 904.9 mi
  • Duration: 5h 43m

What companies run services between Winston-Salem, NC, USA and Iowa, USA?

United Airlines, American Airlines, and Delta fly from Piedmont Triad International Airport (GSO) to Quad City International Airport (MLI) every 2 hours.

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