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How to get fromWinston-Salem to Jacksonvilleby bus (Greyhound, Flixbus), bus, train, car, plane, or bus (Greyhound)

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There are 7 ways to get from Winston-Salem to Jacksonville by bus (Greyhound, Flixbus), bus, train, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Charlotte Bus Station to Jacksonvillebus bus FlixBus 2433
    9h 45m
    $74–130

  2. Bus, train

    1. Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Carytrain train
    3. Take the train from Cary to Jacksonvilletrain train
    14h 32m
    $318–499

  3. Drive  457.3 mi

    1. Drive from Winston-Salem to Jacksonvillecar car 457.3 mi
    7h 39m
    $76–110

  4. Fly from Piedmont Triad International Airport

    1. Fly from Piedmont Triad International Airport (GSO) to Jacksonville (JAX)plane plane GSO - JAX
    6h 49m
    $84–436

  5. Bus via Camden (Greyhound)

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Jacksonvillebus bus
    12h 25m
    $88–131

  6. Bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Jacksonville (JAX)plane plane CLT - JAX
    6h 15m
    $84–459

  7. Bus to Raleigh-Durham International Airport, fly

    1. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Jacksonville (JAX)plane plane RDU - JAX
    7h 43m
    $90–460

Winston-Salem to Jacksonville by bus

Calendar14Weekly Buses
Duration9h 45mAverage Duration
Ticket$74Cheapest Price
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Comparing Your Travel Options

Map of how to get from Winston-Salem to Jacksonville.ExpandLaunch map view
  • Distance: 460 mi
  • Duration: 9h 45m

What companies run services between Winston-Salem, NC, USA and Jacksonville, FL, USA?

You can take a bus from Winston Salem(Trans Center) to Jacksonville via Charlotte Bus Station in around 9h 45m. Alternatively, American Airlines, Delta, and United Airlines fly from Piedmont Triad International Airport (GSO) to Jacksonville (JAX) hourly.

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