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How to get fromWinston-Salem to Kentuckyby bus, plane, bus (Greyhound, Flixbus, Amtrak), train, car, or bus (Greyhound, Amtrak)

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There are 8 ways to get from Winston-Salem to Kentucky by bus, plane, bus (Greyhound, Flixbus, Amtrak), train, car, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Tri-State Airport

    best
    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Tri-State Airport (HTS)plane plane CLT - HTS
    4h 37m
    $90–390

  2. Bus, fly to Blue Grass Airport

    cheapest
    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Blue Grass Airport (LEX)plane plane CLT - LEX
    6h 53m
    $68–357

  3. Bus via Atlanta

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    4. Take the bus from Nashville to Louisville, KYbus bus
    16h 40m
    $112–199

  4. Bus, train

    1. Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Charlottesvilletrain train
    3. Take the train from Charlottesville to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    24h 23m
    $447–752

  5. Drive  421 mi

    1. Drive from Winston-Salem to Louisvillecar car 421 mi
    8h 10m
    $77–111

  6. Bus, fly to Covington

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Covington (CVG)plane plane CLT - CVG
    5h 33m
    $104–630

  7. Bus, fly to Louisville International Airport

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)plane plane CLT - SDF
    5h 48m
    $107–628

  8. Bus

    1. Take the bus from Winston Salem to Columbusbus bus
    2. Take the bus from Columbus to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    18h 35m
    $93–187

Winston-Salem to Kentucky by bus

Calendar14Weekly Buses
Duration16h 40mAverage Duration
Ticket$112Cheapest Price
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Comparing Your Travel Options

Map of how to get from Winston-Salem to Kentucky.ExpandLaunch map view
  • Distance: 333.2 mi
  • Duration: 4h 37m

What companies run services between Winston-Salem, NC, USA and Kentucky, USA?

You can take a bus from Winston Salem(Trans Center) to Louisville, KY via Charlotte Bus Station, Atlanta Bus Station, and Nashville in around 16h 40m.

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