There are 8 ways to get from Winston-Salem to Key West by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Piedmont Triad International Airport
best- Fly from Piedmont Triad International Airport (GSO) to Key West International Airport (EYW)plane GSO - EYW
6h 24m$114–486Bus to Charlotte Douglas International Airport, fly
cheapest- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)plane CLT - EYW
5h 30m$98–419Bus
- Take the bus from Winston Salem(Trans Center) to Fayetteville Bus Stationbus
- Take the bus from Fayetteville Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
27h 21m$170–257Bus, train via Fayetteville
- Take the bus from Winston Salem(Trans Center) to Fayetteville Bus Stationbus
- Take the train from Fayetteville Amtrak Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
30h 8m$503–783Drive 960.1 mi
- Drive from Winston-Salem to Key Westcar 960.1 mi
16h 43m$176–254Bus to Raleigh-Durham International Airport, fly
- Take the bus from Winston Salem(Trans Center) to Durhambus
- Fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW)plane RDU - EYW
6h 57m$99–420Bus to Asheville Regional Airport, fly
- Take the bus from Winston Salem(Trans Center) to Asheville, NCbus
- Fly from Asheville Regional Airport (AVL) to Key West International Airport (EYW)plane AVL - EYW
7h 15m$103–402Bus, train
- Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus
- Take the train from Greensboro to Carytrain
- Take the train from Cary to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
33h 41m$572–967
Winston-Salem to Key West by bus and foot
Comparing Your Travel Options
The cheapest way to get from Winston-Salem to Key West is to bus which costs $170 - $260 and takes 27h 21m.
The fastest way to get from Winston-Salem to Key West is to bus and fly which takes 5h 30m and costs $95 - $420.
No, there is no direct bus from Winston-Salem to Key West. However, there are services departing from Winston Salem(Trans Center) and arriving at N Roosevelt & 3rd Street via Fayetteville Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 27h 21m.
The distance between Winston-Salem and Key West is 836 miles. The road distance is 965.7 miles.
The best way to get from Winston-Salem to Key West without a car is to bus which takes 27h 21m and costs $170 - $260.
It takes approximately 6h 24m to get from Winston-Salem to Key West, including transfers.
Winston-Salem to Key West bus services, operated by Greyhound USA, depart from Winston Salem(Trans Center) station.
The best way to get from Winston-Salem to Key West is to fly which takes 6h 24m and costs $110 - $490. Alternatively, you can bus, which costs $170 - $260 and takes 27h 21m.
Winston-Salem to Key West bus services, operated by Greyhound USA, arrive at Fayetteville Bus Station.
Yes, the driving distance between Winston-Salem to Key West is 966 miles. It takes approximately 16h 43m to drive from Winston-Salem to Key West.
What companies run services between Winston-Salem, NC, USA and Key West, FL, USA?
American Airlines, Delta, and United Airlines fly from Piedmont Triad International Airport (GSO) to Key West International Airport (EYW) every 3 hours. Alternatively, you can take a bus from Winston Salem(Trans Center) to N Roosevelt & 3rd Street via Fayetteville Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 27h 21m.
- Website
- aa.com
Flights from Piedmont Triad International Airport to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $85–450
Flights from Piedmont Triad International Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 57m
- When
- Tuesday
- Estimated price
- $85–450
Flights from Piedmont Triad International Airport to Key West International Airport via Philadelphia
- Ave. Duration
- 7h 54m
- When
- Every day
- Estimated price
- $130–600
Flights from Charlotte Douglas International Airport to Key West International Airport
- Ave. Duration
- 2h 22m
- When
- Every day
- Estimated price
- $70–380
Flights from Charlotte Douglas International Airport to Key West International Airport via Miami
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $70–380
Flights from Raleigh-Durham International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $70–380
Flights from Raleigh-Durham International Airport to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $75–380
Flights from Asheville Regional Airport to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $70–360
- Website
- delta.com
Flights from Piedmont Triad International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $95–480
Flights from Charlotte Douglas International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $75–400
Flights from Raleigh-Durham International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $80–410
Flights from Asheville Regional Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $65–360
- Website
- allegiantair.com
Flights from Asheville Regional Airport to Key West International Airport
- Ave. Duration
- 2h 2m
- When
- Sunday and Thursday
- Estimated price
- $65–350
Flights from Asheville Regional Airport to Key West International Airport via St. Petersburg
- Ave. Duration
- 3h 58m
- When
- Monday and Friday
- Estimated price
- $65–350
- Website
- united.com
Flights from Piedmont Triad International Airport to Key West International Airport via Washington Dulles
- Ave. Duration
- 6h 7m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–550
Flights from Raleigh-Durham International Airport to Key West International Airport via Washington Dulles
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $95–450
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Key West International Airport
- Ave. Duration
- 2h 34m
- When
- Monday and Friday
- Estimated price
- $130–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fayetteville Amtrak Station to Hollywood Amtrak Station
- Ave. Duration
- 16h 54m
- Frequency
- Once daily
- Estimated price
- $450–700
- Website
- Amtrak
Train from Greensboro to Cary
- Ave. Duration
- 1h 27m
- Frequency
- 5 times a day
- Estimated price
- $40–65
- Website
- Amtrak
Train from Cary to Hollywood Amtrak Station
- Ave. Duration
- 21h 30m
- Frequency
- Once daily
- Estimated price
- $500–850
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Fayetteville Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $25–40
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Fayetteville Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $25–40
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $13–20
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Durham
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Asheville, NC
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $25–40
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Greensboro Bus Stop
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- $4–8
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Fayetteville Bus Station to Miami Airport Station
- Ave. Duration
- 15h 15m
- Frequency
- 4 times a week
- Estimated price
- $120–180
- Schedules at
- Flixbus USA
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Book your Winston-Salem to Key West bus tickets online with Omio.
There are 920+ hotels available in Key West.






