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How to get fromWinston-Salem to Lafayetteby plane, bus, train, bus (Greyhound, Amtrak), car, or shuttle

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There are 7 ways to get from Winston-Salem to Lafayette by plane, bus, train, bus (Greyhound, Amtrak), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Piedmont Triad International Airport to Purdue University Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Purdue University Airport (LAF)plane plane GSO - LAF
    8h 36m
    $120–574

  2. Bus

    cheapest
    1. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    2. Take the bus from Columbus to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Lafayette Amtrak Stationbus bus
    16h 50m
    $80–186

  3. Bus, train

    1. Take the bus from Winston Salem(Trans Center) to Ashlandbus bus Charlotte
    2. Take the train from Ashland Amtrak Station to Lafayette Amtrak Stationtrain train Cardinal
    16h 22m
    $127–299

  4. Drive 570.4 mi

    1. Drive from Winston-Salem to Lafayettecar car 570.4 mi
    10h 7m
    $105–151

  5. Bus to Charlotte Douglas International Airport, fly to Indianapolis, shuttle

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Indianapolis (IND)plane plane CLT - IND
    3. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    6h 32m
    $129–663

  6. Bus to Raleigh-Durham International Airport, fly to Indianapolis, shuttle

    1. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Indianapolis (IND)plane plane RDU - IND
    3. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    8h 1m
    $125–614

  7. Fly Piedmont Triad International Airport to Chicago O'Hare International Airport, train

    1. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    8h 50m
    $130–508

Winston-Salem to Lafayette by bus and train

Calendar3Weekly Services
Duration16h 22mAverage Duration
Ticket$127Cheapest Price
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Questions & Answers

Map of how to get from Winston-Salem to Lafayette.ExpandLaunch map view
  • Distance: 508.7 mi
  • Duration: 8h 36m

What companies run services between Winston-Salem, NC, USA and Lafayette, IN, USA?

United Airlines and American Airlines fly from Piedmont Triad International Airport (GSO) to Purdue University Airport (LAF) 4 times a day. Alternatively, you can take a bus from Winston Salem(Trans Center) to Lafayette Amtrak Station via Columbus and Indianapolis Union Station in around 16h 50m.

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