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How to get fromWinston-Salem to Lexingtonby plane, bus (Greyhound), car, or bus

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There are 8 ways to get from Winston-Salem to Lexington by plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Piedmont Triad International Airport to Blue Grass Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Blue Grass Airport (LEX)plane plane GSO - LEX
    7h 33m
    $160–924

  2. Drive 348.9 mi

    cheapest
    1. Drive from Winston-Salem to Lexingtoncar car 348.9 mi
    7h
    $64–92

  3. Bus via Charleston

    1. Take the bus from Winston Salem(Trans Center) to Charleston, WVbus bus
    2. Take the bus from Charleston Bus Station to Wilson & Ferrell Shell Station - Columbusbus bus
    3. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Cincinnati, OHbus bus
    4. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus
    14h 32m
    $121–244

  4. Bus to Charlotte Douglas International Airport, fly to Louisville International Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)plane plane CLT - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    6h 2m
    $137–616

  5. Bus to Charlotte Douglas International Airport, fly to Blue Grass Airport

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Blue Grass Airport (LEX)plane plane CLT - LEX
    7h
    $155–847

  6. Bus to Charlotte Douglas International Airport, fly to Mcghee Tyson Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Mcghee Tyson Airport (TYS)plane plane CLT - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Lexingtoncar car
    7h 35m
    $153–745

  7. Bus

    1. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    2. Take the bus from Columbus to Cincinnatibus bus
    3. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus
    15h 17m
    $97–181

  8. Bus #2

    1. Take the bus from Winston Salem to Columbusbus bus
    2. Take the bus from Columbus to Cincinnatibus bus
    3. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus
    17h 18m
    $155–242

Winston-Salem to Lexington by bus and taxi

Calendar7Weekly Services
Duration17h 18mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from Winston-Salem to Lexington.ExpandLaunch map view
  • Distance: 327.3 mi
  • Duration: 7h 33m

What companies run services between Winston-Salem, NC, USA and Lexington, KY, USA?

American Airlines, Delta, and United Airlines fly from Piedmont Triad International Airport (GSO) to Blue Grass Airport (LEX) hourly. Alternatively, you can take a bus from Winston Salem(Trans Center) to Lexington via Charleston Bus Station, N Wilson Rd & Ferrell Pl - Columbus, Cincinnati, OH, Cincinnati Bus Station, and Lexington Bus Stop in around 14h 32m.

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