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How to get fromWinston-Salem to Lexingtonby plane, bus, or car

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There are 9 ways to get from Winston-Salem to Lexington by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Piedmont Triad International Airport to Blue Grass Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Blue Grass Airport (LEX)plane plane GSO - LEX
    7h 28m
    $86–444

  2. Drive  348.9 mi

    cheapest
    1. Drive from Winston-Salem to Lexingtoncar car 348.9 mi
    7h
    $64–92

  3. Bus, drive

    1. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    2. Take the bus from Columbus to Louisvillebus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    18h 23m
    $83–175

  4. Bus to Charlotte Douglas International Airport, fly to Louisville International Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)plane plane CLT - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    6h 12m
    $114–646

  5. Bus to Charlotte Douglas International Airport, fly to Covington, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Covington (CVG)plane plane CLT - CVG
    3. Drive from Covington (CVG) to Lexingtoncar car
    6h 13m
    $115–647

  6. Bus to Charlotte Douglas International Airport, fly to Blue Grass Airport

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Blue Grass Airport (LEX)plane plane CLT - LEX
    7h 8m
    $67–377

  7. Bus to Charlotte Douglas International Airport, fly to Tri-State Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Tri-State Airport (HTS)plane plane CLT - HTS
    3. Drive from Tri-State Airport (HTS) to Lexingtoncar car
    6h 38m
    $81–400

  8. Bus to Charlotte Douglas International Airport, fly to Mcghee Tyson Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Mcghee Tyson Airport (TYS)plane plane CLT - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Lexingtoncar car
    7h 39m
    $135–775

  9. Bus, drive via Atlanta

    1. Take the bus from Winston Salem(Trans Center) to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Louisville Bus Stationbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    20h 43m
    $125–249

Piedmont Triad International Airport (GSO) to Blue Grass Airport (LEX) flights

Calendar98Weekly Planes
Duration4h 40mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

Map of how to get from Winston-Salem to Lexington.ExpandLaunch map view
  • Distance: 327.3 mi
  • Duration: 7h 28m

What companies run services between Winston-Salem, NC, USA and Lexington, KY, USA?

Delta, American Airlines, and United Airlines fly from Piedmont Triad International Airport (GSO) to Blue Grass Airport (LEX) hourly.

Airlines
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