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How to get fromWinston-Salem to Mechanicsburgby plane, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound)

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There are 8 ways to get from Winston-Salem to Mechanicsburg by plane, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Piedmont Triad International Airport to Harrisburg International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Harrisburg International Airport (MDT)plane plane GSO - MDT
    6h 59m
    $86–446

  2. Drive 382.9 mi

    cheapest
    1. Drive from Winston-Salem to Mechanicsburgcar car 382.9 mi
    7h 2m
    $70–101

  3. Bus (Greyhound)

    1. Take the bus from Winston Salem(Trans Center) to Baltimore Downtown Bus Stationbus bus Greyhound US0670
    2. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus Greyhound US0430
    13h 14m
    $72–137

  4. Train, bus

    1. Take the train from High Point to Washington Union Stationtrain train Crescent / ...
    2. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus Greyhound US0430
    13h 43m
    $116–241

  5. Bus to Charlotte Douglas International Airport, fly to Harrisburg International Airport

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Harrisburg International Airport (MDT)plane plane CLT - MDT
    6h 31m
    $82–442

  6. Fly Piedmont Triad International Airport to Philadelphia International Airport, train

    1. Fly from Piedmont Triad International Airport (GSO) to Philadelphia International Airport (PHL)plane plane GSO - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    7h 46m
    $148–698

  7. Bus, train

    1. Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Harrisburgtrain train
    14h 47m
    $165–360

  8. Bus via Fredericksburg

    1. Take the bus from Greensboro Bus Stop to Fredericksburgbus bus
    2. Take the bus from Fredericksburg to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus
    17h 34m
    $86–152

Winston-Salem to Mechanicsburg by bus and foot (Greyhound)

Calendar14Weekly Services
Duration13h 14mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Winston-Salem to Mechanicsburg.ExpandLaunch map view
  • Distance: 373.9 mi
  • Duration: 6h 59m

What companies run services between Winston-Salem, NC, USA and Mechanicsburg, Cumberland County, PA, USA?

United Airlines, American Airlines, and two other airlines fly from Piedmont Triad International Airport (GSO) to Harrisburg International Airport (MDT) hourly. Alternatively, you can take a bus from Winston Salem(Trans Center) to E Main St & Arch St WB via Baltimore Downtown Bus Station, Harrisburg Bus Station, and Market Square Transfer Center in around 13h 14m.

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