There are 5 ways to get from Winston-Salem to Mobile by plane, bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Piedmont Triad International Airport
best- Fly from Piedmont Triad International Airport (GSO) to Mobile Regional Airport (MOB)plane GSO - MOB
6h 1m$134–542Bus (Greyhound)
cheapest- Take the bus from Winston Salem(Trans Center) to Atlanta Bus Stationbus Greyhound US0670
- Take the bus from Atlanta Bus Station to Mobile Bus Stationbus Greyhound US0602 / ...
14h 56m$102–167Bus via Charlotte
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Atlanta Downtownbus
- Take the bus from Atlanta to Grand Baybus
- Take the bus from Grand Bay to Mobilebus
14h 48m$160–227Drive 634.6 mi
- Drive from Winston-Salem to Mobilecar 634.6 mi
11h$116–168Bus to Charlotte Douglas International Airport, fly
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Mobile Regional Airport (MOB)plane CLT - MOB
5h 35m$110–452
Winston-Salem to Mobile by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Winston-Salem to Mobile is to bus which costs $100 - $170 and takes 14h 56m.
The fastest way to get from Winston-Salem to Mobile is to bus and fly which takes 5h 35m and costs $110 - $460.
No, there is no direct bus from Winston-Salem to Mobile. However, there are services departing from Winston Salem(Trans Center) and arriving at Mobile via Charlotte Bus Station, Atlanta and Grand Bay. The journey, including transfers, takes approximately 14h 48m.
The distance between Winston-Salem and Mobile is 649 miles. The road distance is 638.4 miles.
The best way to get from Winston-Salem to Mobile without a car is to bus via Charlotte which takes 14h 48m and costs $160 - $230.
It takes approximately 6h 1m to get from Winston-Salem to Mobile, including transfers.
Winston-Salem to Mobile bus services, operated by Greyhound USA, depart from Winston Salem(Trans Center) station.
The best way to get from Winston-Salem to Mobile is to fly which takes 6h 1m and costs $130 - $550. Alternatively, you can bus via Charlotte, which costs $160 - $230 and takes 14h 48m.
Winston-Salem to Mobile bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Mobile is 1h behind Winston-Salem. It is currently 12:43 PM in Winston-Salem and 11:43 AM in Mobile.
What companies run services between Winston-Salem, NC, USA and Mobile, AL, USA?
Delta, American Airlines, and United Airlines fly from Piedmont Triad International Airport (GSO) to Mobile Regional Airport (MOB) every 3 hours. Alternatively, you can take a bus from Winston Salem(Trans Center) to Mobile via Charlotte Bus Station, Atlanta Downtown, Civic Center Station, Doraville Station, Atlanta, and Grand Bay in around 14h 48m.
- Website
- aa.com
Flights from Piedmont Triad International Airport to Mobile Regional Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $85–480
Flights from Piedmont Triad International Airport to Mobile Regional Airport via Reagan Washington, Charlotte Douglas International Airport
- Ave. Duration
- 7h 12m
- When
- Every day
- Estimated price
- $120–600
Flights from Charlotte Douglas International Airport to Mobile Regional Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $65–390
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $12–19
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $12–19
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Atlanta Bus Station
- Ave. Duration
- 6h 55m
- Frequency
- 3 times a day
- Estimated price
- $50–85
- Website
- Greyhound
Bus from Atlanta Bus Station to Mobile Bus Station
- Ave. Duration
- 5h 45m
- Frequency
- 5 times a day
- Estimated price
- $50–85
- Website
- Greyhound
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Booking & Getting There
Yes, the driving distance between Winston-Salem to Mobile is 638 miles. It takes approximately 11h to drive from Winston-Salem to Mobile.
Book your Winston-Salem to Mobile bus tickets online with Omio.
There are 193+ hotels available in Mobile.


