There are 10 ways to get from Winston-Salem to Niagara Falls by plane, bus, train (Amtrak), car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Piedmont Triad International Airport to Buffalo Niagara International Airport, bus
best- Fly from Piedmont Triad International Airport (GSO) to Buffalo Niagara International Airport (BUF)plane GSO - BUF
- Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus
7h 15m$124–630Bus
cheapest- Take the bus from Winston Salem to Charlestonbus
- Take the bus from Charleston to Clevelandbus
- Take the bus from Cleveland to Buffalobus
17h 48m$71–194Train (Amtrak)
- Take the train from High Point to Ny Moynihan Train Hall At Penn Stationtrain Crescent / ...
- Take the train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Stationtrain Empire Service / ...
23h 22m$532–852Drive 620.4 mi
- Drive from Winston-Salem to Niagara Fallscar 620.4 mi
10h 52m$106–154Bus to Charlotte Douglas International Airport, fly to Buffalo Niagara International Airport, bus
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF)plane CLT - BUF
- Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus
6h 33m$123–635Bus to Raleigh-Durham International Airport, fly to Buffalo Niagara International Airport, bus
- Take the bus from Winston Salem(Trans Center) to Durhambus
- Fly from Raleigh-Durham International Airport (RDU) to Buffalo Niagara International Airport (BUF)plane RDU - BUF
- Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus
7h 47m$144–246Bus to Charlotte Douglas International Airport, fly to Rochester, bus
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Rochester (ROC)plane CLT - ROC
- Take the bus from Rochester Bus Stop to Niagara Falls USAbus
8h$181–872Bus to Charlotte Douglas International Airport, fly to Toronto Pearson International Airport, bus
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Toronto Pearson International Airport (YYZ)plane CLT - YYZ
- Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus
8h 42m$95–401Train via Winston-Salem Transportation Center (Amtrak)
- Take the train from High Point to Ny Moynihan Train Hall At Penn Stationtrain Crescent / ...
- Take the train from Ny Moynihan Train Hall At Penn Station to Canadian Bordertrain Maple Leaf
24h$533–855Bus via Washington
- Take the bus from Winston Salem(Trans Center) to Washington Union Stationbus
- Take the bus from Washington Union Station to Pittsburgh Intermodal Stationbus
- Take the bus from Pittsburgh, Pa to Buffalo, Nybus 510
25h 28m$149–355
Winston-Salem to Niagara Falls by bus
Comparing Your Travel Options
The cheapest way to get from Winston-Salem to Niagara Falls is to bus which costs $70 - $200 and takes 17h 48m.
The fastest way to get from Winston-Salem to Niagara Falls is to bus and fly which takes 6h 33m and costs $120 - $650.
No, there is no direct bus from Winston-Salem to Niagara Falls. However, there are services departing from Baptist Hospital and arriving at Main Street & Pine Avenue via Winston Salem, Charleston, Cleveland and Ellicott Street & MTC Static. The journey, including transfers, takes approximately 17h 48m.
No, there is no direct train from Winston-Salem to Niagara Falls station. However, there are services departing from High Point and arriving at Niagara Falls Amtrak Station via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 23h 22m.
The distance between Winston-Salem and Niagara Falls is 534 miles. The road distance is 624.1 miles.
The best way to get from Winston-Salem to Niagara Falls without a car is to bus which takes 17h 48m and costs $70 - $200.
It takes approximately 7h 15m to get from Winston-Salem to Niagara Falls, including transfers.
Winston-Salem to Niagara Falls bus services, operated by Barons Bus, depart from Winston Salem station.
Winston-Salem to Niagara Falls train services, operated by Amtrak, depart from High Point station.
The best way to get from Winston-Salem to Niagara Falls is to bus which takes 17h 48m and costs $70 - $200. Alternatively, you can train, which costs $500 - $850 and takes 23h 22m.
What companies run services between Winston-Salem, NC, USA and Niagara Falls, NY, USA?
You can take a bus from Baptist Hospital to Main Street & Pine Avenue via Winston Salem, Charleston, Cleveland, and Ellicott Street & MTC Static in around 17h 48m. Alternatively, you can take a bus from Martin Luther King Jr Drive at Rams Drive to Niagara Falls Amtrak Station via High Point Terminal, High Point, and Ny Moynihan Train Hall At Penn Station in around 23h 22m.
- Website
- aa.com
Flights from Piedmont Triad International Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $110–650
Flights from Piedmont Triad International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $100–600
Flights from Piedmont Triad International Airport to Buffalo Niagara International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $110–650
Flights from Piedmont Triad International Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 6h 26m
- When
- Every day
- Estimated price
- $120–650
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $100–600
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $120–700
Flights from Raleigh-Durham International Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 3h 54m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–650
Flights from Raleigh-Durham International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 3h 59m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–650
Flights from Raleigh-Durham International Airport to Buffalo Niagara International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $120–700
Flights from Charlotte Douglas International Airport to Rochester
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $130–800
Flights from Charlotte Douglas International Airport to Rochester via Philadelphia
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $150–850
Flights from Charlotte Douglas International Airport to Toronto Pearson International Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $60–350
- Website
- united.com
Flights from Piedmont Triad International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 59m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $100–600
Flights from Piedmont Triad International Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $120–650
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $110–650
Flights from Raleigh-Durham International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $100–650
Flights from Raleigh-Durham International Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 4h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Charlotte Douglas International Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $140–800
Flights from Charlotte Douglas International Airport to Toronto Pearson International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $60–350
Flights from Charlotte Douglas International Airport to Toronto Pearson International Airport via Washington Dulles
- Ave. Duration
- 3h 57m
- When
- Saturday
- Estimated price
- $65–360
- Website
- delta.com
Flights from Piedmont Triad International Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $120–650
Flights from Piedmont Triad International Airport to Buffalo Niagara International Airport via Atlanta
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $140–750
Flights from Piedmont Triad International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 58m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
- Website
- southwest.com
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $110–650
Flights from Raleigh-Durham International Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $100–650
Flights from Charlotte Douglas International Airport to Rochester via Baltimore
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $140–800
- Website
- aircanada.com
Flights from Charlotte Douglas International Airport to Toronto Pearson International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $60–350
Flights from Charlotte Douglas International Airport to Toronto Pearson International Airport via Washington Dulles
- Ave. Duration
- 3h 57m
- When
- Saturday
- Estimated price
- $65–360
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 45m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,400
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from High Point to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 11h 41m
- Frequency
- Twice daily
- Estimated price
- $280–450
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Station
- Ave. Duration
- 9h 8m
- Frequency
- 3 times a day
- Estimated price
- $250–400
- Website
- Amtrak
Train from High Point to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 11h 41m
- Frequency
- Twice daily
- Estimated price
- $280–450
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Canadian Border
- Ave. Duration
- 9h 36m
- Frequency
- Once daily
- Estimated price
- $250–400
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo Niagara International Airport to Niagara Falls USA
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $5–8
- Schedules at
- Flixbus USA
Bus from Buffalo Niagara International Airport to Niagara Falls USA
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $5–8
- Schedules at
- Flixbus USA
Bus from Buffalo Niagara International Airport to Niagara Falls USA
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $5–8
- Schedules at
- Flixbus USA
Bus from Rochester Bus Stop to Niagara Falls USA
- Ave. Duration
- 2h 5m
- Frequency
- Hourly
- Estimated price
- $15–23
- Schedules at
- Flixbus USA
Bus from Washington Union Station to Pittsburgh Intermodal Station
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Winston Salem to Charleston
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $21–60
- Website
- Barons Bus
Bus from Charleston to Cleveland
- Ave. Duration
- 5h 55m
- Frequency
- Once daily
- Estimated price
- $28–70
- Website
- Barons Bus
Bus from Cleveland to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- Barons Bus
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Durham
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $14–22
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Washington Union Station
- Ave. Duration
- 8h 30m
- Frequency
- 4 times a day
- Estimated price
- $65–100
- Website
- Greyhound
Bus from Washington Union Station to Pittsburgh Intermodal Station
- Ave. Duration
- 5h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–65
- Website
- Greyhound
- Phone
- +1 866 488 4452
- [email protected]
- Website
- Megabus
Bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminal
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- $10–14
- Website
- Megabus
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Pittsburgh, Pa to Buffalo, Ny
- Saver
- $45–180
- Flexible
- $80–190
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Booking & Getting There
Winston-Salem to Niagara Falls bus services, operated by Barons Bus, arrive at Charleston station.
Winston-Salem to Niagara Falls train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Winston-Salem to Niagara Falls is 624 miles. It takes approximately 10h 52m to drive from Winston-Salem to Niagara Falls.
Book your Winston-Salem to Niagara Falls train tickets online with Omio.
Book your Winston-Salem to Niagara Falls bus tickets online with Omio.
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