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How to get fromWinston-Salem to Pittsburghby plane, bus (Greyhound), bus, train, or car

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There are 8 ways to get from Winston-Salem to Pittsburgh by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Piedmont Triad International Airport to Pittsburgh International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Pittsburgh International Airport (PIT)plane plane GSO - PIT
    6h 38m
    $104–572

  2. Bus

    cheapest
    1. Take the bus from Winston Salem to Charlestonbus bus
    2. Take the bus from Charleston to Morgantown Mt Linebus bus
    3. Take the bus from Westover Terminal to Pittsburgh Greyhoundbus bus
    13h 10m
    $41–147

  3. Bus via Cambridge

    1. Take the bus from Winston Salem to Charlestonbus bus
    2. Take the bus from Charleston to Cambridgebus bus
    3. Take the bus from Cambridge, OH to Pittsburgh Intermodal Stationbus bus
    12h 10m
    $54–144

  4. Bus, train

    1. Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Pittsburgh Amtrak Stationtrain train
    18h 45m
    $365–577

  5. Drive  390 mi

    1. Drive from Winston-Salem to Pittsburghcar car 390 mi
    6h 51m
    $72–103

  6. Bus to Charlotte Douglas International Airport, fly to Pittsburgh International Airport

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Pittsburgh International Airport (PIT)plane plane CLT - PIT
    5h 56m
    $81–455

  7. Bus to Raleigh-Durham International Airport, fly to Pittsburgh International Airport

    1. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Pittsburgh International Airport (PIT)plane plane RDU - PIT
    7h 10m
    $82–456

  8. Bus to Charlotte Douglas International Airport, fly to Altoona–Blair County Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Altoona–Blair County Airport (AOO)plane plane CLT - AOO
    3. Drive from Altoona–Blair County Airport (AOO) to Pittsburghcar car
    7h 5m
    $174–602

Winston-Salem to Pittsburgh by bus

Calendar7Weekly Buses
Duration12h 10mAverage Duration
Ticket$54Cheapest Price
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Comparing Your Travel Options

Map of how to get from Winston-Salem to Pittsburgh.ExpandLaunch map view
  • Distance: 352.9 mi
  • Duration: 6h 38m

What companies run services between Winston-Salem, NC, USA and Pittsburgh, PA, USA?

American Airlines, United Airlines, and Delta fly from Piedmont Triad International Airport (GSO) to Pittsburgh International Airport (PIT) hourly. Alternatively, you can take a bus from Baptist Hospital to Pittsburgh Intermodal Station via Winston Salem, Charleston, and Cambridge, OH in around 12h 10m.

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