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How to get fromWinston-Salem to Portlandby plane, bus (Flixbus, Amtrak), bus, train, car, or bus (Greyhound, Amtrak)

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There are 8 ways to get from Winston-Salem to Portland by plane, bus (Flixbus, Amtrak), bus, train, car, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Piedmont Triad International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Portland (PWM)plane plane GSO - PWM
    5h 42m
    $128–622

  2. Bus to Charlotte Douglas International Airport, fly

    cheapest
    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Portland (PWM)plane plane CLT - PWM
    5h 28m
    $125–628

  3. Bus via New York

    1. Take the bus from Winston-Salem, NC to New York, NYbus bus
    2. Take the bus from NYC Downtown to Bostonbus bus
    3. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    19h 30m
    $132–214

  4. Bus, train

    1. Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    4. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    19h 36m
    $255–553

  5. Drive 837.4 mi

    1. Drive from Winston-Salem to Portlandcar car 837.4 mi
    15h 52m
    $153–221

  6. Bus to Raleigh-Durham International Airport, fly

    1. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Portland (PWM)plane plane RDU - PWM
    6h 18m
    $166–679

  7. Bus

    1. Take the bus from Winston Salem(Trans Center) to Port Authority Bus Terminalbus bus
    2. Take the bus from Port Authority Bus Terminal to Bostonbus bus
    3. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    21h 52m
    $147–291

  8. Train, bus

    1. Take the train from High Point to Lynchburgtrain train
    2. Take the train from Lynchburg to Bostontrain train
    3. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    23h 59m
    $264–554

Winston-Salem to Portland by bus and train

Calendar14Weekly Services
Duration19h 36mAverage Duration
Ticket$255Cheapest Price
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Questions & Answers

Map of how to get from Winston-Salem to Portland.ExpandLaunch map view
  • Distance: 752.1 mi
  • Duration: 5h 42m

What companies run services between Winston-Salem, NC, USA and Portland, ME, USA?

United Airlines, American Airlines, and Delta fly from Piedmont Triad International Airport (GSO) to Portland (PWM) hourly. Alternatively, you can take a bus from Winston-Salem, NC to Portland, ME via New York, NY, NYC Downtown, Boston, and Boston, MA - South Station in around 19h 30m.

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