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How to get fromWinston-Salem to Saint Simons Islandby bus (Greyhound, Flixbus), bus, train, taxi, car, or plane

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There are 7 ways to get from Winston-Salem to Saint Simons Island by bus (Greyhound, Flixbus), bus, train, taxi, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Winston Salem(Trans Center) to Raleigh Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Raleigh Bus Station to Brunswickbus bus FlixBus N2472
    10h 40m
    $114–173

  2. Drive  402.2 mi

    cheapest
    1. Drive from Winston-Salem to Saint Simons Islandcar car 402.2 mi
    6h 51m
    $69–100

  3. Bus, train, taxi

    1. Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Carytrain train
    3. Take the train from Cary to Savannah Stationtrain train
    4. Take the train from Savannah Station to Jesup Stationtrain train
    5. Take the taxi from Jesup Station to Saint Simons Islandtaxi taxi
    14h 5m
    $365–553

  4. Fly Piedmont Triad International Airport to Brunswick Golden Isles Airport

    1. Fly from Piedmont Triad International Airport (GSO) to Brunswick Golden Isles Airport (BQK)plane plane GSO - BQK
    6h 48m
    $118–442

  5. Bus via Fayetteville

    1. Take the bus from Winston Salem(Trans Center) to Fayetteville Bus Stationbus bus Greyhound US0647S
    2. Take the bus from Fayetteville Bus Station to Brunswickbus bus FlixBus N2472
    11h 25m
    $112–169

  6. Bus to Charlotte Douglas International Airport, fly to Savannah, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Savannah (SAV)plane plane CLT - SAV
    3. Drive from Savannah (SAV) to Saint Simons Islandcar car
    5h 39m
    $111–597

  7. Bus to Charlotte Douglas International Airport, fly to Hilton Head Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Hilton Head Airport (HHH)plane plane CLT - HHH
    3. Drive from Hilton Head Airport (HHH) to Saint Simons Islandcar car
    6h 37m
    $83–396

Piedmont Triad International Airport (GSO) to Brunswick Golden Isles Airport (BQK) flights

Calendar21Weekly Planes
Duration5h 3mAverage Duration
Ticket$64Cheapest Price
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Comparing Your Travel Options

Map of how to get from Winston-Salem to Saint Simons Island.ExpandLaunch map view
  • Distance: 513.8 mi
  • Duration: 10h 40m

What companies run services between Winston-Salem, NC, USA and Saint Simons Island, GA, USA?

You can take a bus from Winston Salem(Trans Center) to Saint Simons Island via Raleigh Bus Station and Brunswick in around 10h 40m. Alternatively, Delta flies from Piedmont Triad International Airport (GSO) to Brunswick Golden Isles Airport (BQK) 3 times a day.

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