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How to get fromWinston-Salem to Santeeby bus, taxi, car, or plane

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There are 6 ways to get from Winston-Salem to Santee by bus, taxi, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    3. Take the taxi from Sumter Bus Stop to Santeetaxi taxi
    5h 42m
    $136–202

  2. Drive 208.1 mi

    cheapest
    1. Drive from Winston-Salem to Santeecar car 208.1 mi
    4h 36m
    $38–55

  3. Bus, fly to Columbia, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Columbia (CAE)plane plane CLT - CAE
    3. Drive from Columbia-Airport-CAE to Santeecar car
    5h 13m
    $125–894

  4. Bus, fly to Charleston International Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Charleston International Airport (CHS)plane plane CLT - CHS
    3. Drive from Charleston-Airport-CHS to Santeecar car
    5h 18m
    $75–404

  5. Bus, fly to Augusta Regional Airport At Bush Field, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Augusta Regional Airport At Bush Field (AGS)plane plane CLT - AGS
    3. Drive from Augusta Regional Airport At Bush Field (AGS) to Santeecar car
    6h 31m
    $78–395

  6. Bus, fly to Florence Regional Airport, taxi

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Florence Regional Airport (FLO)plane plane CLT - FLO
    3. Take the bus from Florence Bus Station to Sumter Bus Stopbus bus
    4. Take the taxi from Sumter Bus Stop to Santeetaxi taxi
    7h 4m
    $182–535

Charlotte Douglas International Airport (CLT) to Columbia (CAE) flights

Calendar57Weekly Planes
Duration1h 4mAverage Duration
Ticket$106Cheapest Price
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Questions & Answers

Map of how to get from Winston-Salem to Santee.ExpandLaunch map view
  • Distance: 217.6 mi
  • Duration: 5h 42m

What companies run services between Winston-Salem, NC, USA and Santee, SC, USA?

There is no direct connection from Winston-Salem to Santee. However, you can take the bus to Charlotte Bus Station, take the bus to Sumter Bus Stop, then take the taxi to Santee. Alternatively, you can drive from Winston-Salem to Santee in around 4h 36m.

Airlines
Bus operators
Other operators

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