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How to get fromWinston-Salem to Sikestonby bus, plane, taxi, car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Winston-Salem to Sikeston by bus, plane, taxi, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Charlotte Douglas International Airport, fly to Lambert–St. Louis International Airport, bus, taxi

    best
    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    4. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    9h 29m
    $247–837

  2. Drive 606.8 mi

    cheapest
    1. Drive from Winston-Salem to Sikestoncar car 606.8 mi
    11h 14m
    $111–160

  3. Bus, drive via Charlotte

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Atlanta Downtownbus bus
    3. Take the bus from Atlanta Bus Station to Paducah Bus Stationbus bus
    4. Drive from Paducah Bus Station to Sikestoncar car
    16h 1m
    $121–218

  4. Fly Piedmont Triad International Airport to Cape Girardeau Municipal Airport, taxi

    1. Fly from Piedmont Triad International Airport (GSO) to Cape Girardeau Municipal Airport (CGI)plane plane GSO - CGI
    2. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi taxi
    8h 17m
    $218–722

  5. Bus to Charlotte Douglas International Airport, fly to Nashville, bus, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Nashville (BNA)plane plane CLT - BNA
    3. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    4. Drive from Paducah Bus Station to Sikestoncar car
    9h 59m
    $440–888

  6. Bus to Charlotte Douglas International Airport, fly to Memphis, bus

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Memphis (MEM)plane plane CLT - MEM
    3. Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus bus
    10h 9m
    $241–985

  7. Bus, drive

    1. Take the bus from Winston Salem(Trans Center) to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Paducah Bus Stationbus bus
    3. Drive from Paducah Bus Station to Sikestoncar car
    16h 17m
    $124–226

  8. Bus

    1. Take the bus from Winston Salem(Trans Center) to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Tornado Bus Co - Nashville to Tornado Bus Co - West Memphisbus bus
    4. Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus bus
    21h 17m
    $219–516

Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL) flights

Calendar56Weekly Planes
Duration2h 58mAverage Duration
Ticket$123Cheapest Price
See schedules

Questions & Answers

Map of how to get from Winston-Salem to Sikeston.ExpandLaunch map view
  • Distance: 819.1 mi
  • Duration: 9h 29m

What companies run services between Winston-Salem, NC, USA and Sikeston, MO, USA?

You can take a bus from Winston Salem(Trans Center) to Sikeston via Atlanta Bus Station, Nashville Bus Station, Fulton Station Outbound, Walmart Station Outbound, Tornado Bus Co - Nashville, Tornado Bus Co - West Memphis, and Flying J - Matthews in around 21h 17m.

Airlines
Bus operators
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