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How to get fromWinston-Salem to South Carolinaby bus, plane, taxi, train, car, or bus (Greyhound)

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There are 7 ways to get from Winston-Salem to South Carolina by bus, plane, taxi, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 1 bus to Piedmont Triad International Airport, fly, taxi

    best
    1. Take the bus from Winston-Salem Transportation Center to Coble Transportation Centerbus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Charlotte Douglas International Airport (CLT)plane plane GSO - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    3h 12m
    $164–672

  2. Drive 283 mi

    cheapest
    1. Drive from Winston-Salem to Charlestoncar car 283 mi
    4h 53m
    $52–75

  3. Bus, train

    1. Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Selma Stationtrain train
    3. Take the train from Selma Station to Charleston Amtrak Stationtrain train
    9h 33m
    $139–273

  4. Bus, train via Fayetteville

    1. Take the bus from Winston Salem(Trans Center) to Raleigh Bus Stationbus bus
    2. Take the bus from Raleigh Bus Station to Fayetteville Bus Stationbus bus
    3. Take the train from Fayetteville Amtrak Station to Charleston Amtrak Stationtrain train
    10h 20m
    $84–173

  5. Bus, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Greenville–Spartanburg International Airport (GSP)plane plane CLT - GSP
    4h 19m
    $111–553

  6. Bus, train via Fayetteville #2

    1. Take the bus from Winston Salem(Trans Center) to Fayetteville Bus Stationbus bus Greyhound US0647S
    2. Take the train from Fayetteville Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    10h 42m
    $83–157

  7. Bus (Greyhound)

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Charlotte Bus Station to Charleston Bus Stationbus bus Greyhound US0643S
    10h 46m
    $56–111

Winston-Salem to South Carolina by bus and train

Calendar14Weekly Services
Duration10h 20mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

Map of how to get from Winston-Salem to South Carolina.ExpandLaunch map view
  • Distance: 134.7 mi
  • Duration: 3h 12m

What companies run services between Winston-Salem, NC, USA and South Carolina, USA?

You can take a bus from Winston Salem(Trans Center) to Broad St / Meeting St via Charlotte Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, Rivers Ave / Cosgrove Ave, Transit Mall, and Visitors Center on John St in around 10h 46m.

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