There are 10 ways to get from Winston-Salem to Syracuse by plane, bus, train (Amtrak), car, train, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Piedmont Triad International Airport to Syracuse Hancock International Airport
best- Fly from Piedmont Triad International Airport (GSO) to Syracuse Hancock International Airport (SYR)plane GSO - SYR
7h 5m$160–880Fly Piedmont Triad International Airport to Ithaca Tompkins Regional Airport, bus
cheapest- Fly from Piedmont Triad International Airport (GSO) to Ithaca Tompkins Regional Airport (ITH)plane GSO - ITH
- Take the bus from Ithaca to Syracuse Bus Stationbus
9h 5m$102–498Bus via New York
- Take the bus from Winston-Salem, NC to New York, NYbus Winston-Salem
- Take the bus from New York to Syracusebus Adt N816 / ...
17h 34m$124–292Train (Amtrak)
- Take the train from High Point to Ny Moynihan Train Hall At Penn Stationtrain Crescent / ...
- Take the train from Ny Moynihan Train Hall At Penn Station to Syracuse Regional Transportation Centertrain Empire Service / ...
20h 3m$248–534Drive 617.4 mi
- Drive from Winston-Salem to Syracusecar 617.4 mi
12h 21m$113–163Bus to Charlotte Douglas International Airport, fly to Syracuse Hancock International Airport
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Syracuse Hancock International Airport (SYR)plane CLT - SYR
6h 47m$166–886Bus to Raleigh-Durham International Airport, fly to Syracuse Hancock International Airport
- Take the bus from Winston Salem(Trans Center) to Durhambus
- Fly from Raleigh-Durham International Airport (RDU) to Syracuse Hancock International Airport (SYR)plane RDU - SYR
7h 43m$137–737Bus to Charlotte Douglas International Airport, fly to Rochester, train
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Rochester (ROC)plane CLT - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
7h 22m$194–1,020Bus
- Take the bus from Winston Salem(Trans Center) to Newark Penn Stationbus Greyhound US0670
- Take the bus from Newark Penn Station to Syracuse Bus Stationbus FlixBus 2685 / ...
18h 55m$122–234Bus, train
- Take the bus from Winston Salem(Trans Center) to Greensboro Bus Stopbus
- Take the train from Greensboro to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Albany-Rensselaer Amtrak Stationtrain
- Take the train from Albany-Rensselaer Amtrak Station to Syracuse Regional Transportation Centertrain
20h 5m$234–623
Winston-Salem to Syracuse by bus and train (Amtrak)
Questions & Answers
The cheapest way to get from Winston-Salem to Syracuse is to drive which costs $110 - $170 and takes 12h 21m.
The fastest way to get from Winston-Salem to Syracuse is to bus and fly which takes 6h 47m and costs $160 - $900.
No, there is no direct bus from Winston-Salem to Syracuse. However, there are services departing from Winston-Salem, NC and arriving at Syracuse via New York. The journey, including transfers, takes approximately 17h 34m.
No, there is no direct train from Winston-Salem to Syracuse. However, there are services departing from High Point and arriving at Syracuse Regional Transportation Center via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 20h 3m.
The distance between Winston-Salem and Syracuse is 564 miles. The road distance is 621 miles.
The best way to get from Winston-Salem to Syracuse without a car is to bus via New York which takes 17h 34m and costs $120 - $300.
It takes approximately 7h 5m to get from Winston-Salem to Syracuse, including transfers.
Winston-Salem to Syracuse bus services, operated by Wanda Coach, depart from Winston-Salem, NC station.
Winston-Salem to Syracuse train services, operated by Amtrak, depart from High Point station.
The best way to get from Winston-Salem to Syracuse is to fly which takes 7h 5m and costs $160 - $900. Alternatively, you can bus via New York, which costs $120 - $300 and takes 17h 34m, you could also train, which costs $240 - $550 and takes 20h 3m.
What companies run services between Winston-Salem, NC, USA and Syracuse, NY, USA?
United Airlines, American Airlines, and Delta fly from Piedmont Triad International Airport (GSO) to Syracuse Hancock International Airport (SYR) hourly. Alternatively, you can take a bus from Winston-Salem, NC to Syracuse via New York, NY, East Broadway, 47-50 Sts-Rockefeller Ctr, and New York in around 17h 34m.
- Website
- aa.com
Flights from Piedmont Triad International Airport to Syracuse Hancock International Airport via Philadelphia
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $150–900
Flights from Piedmont Triad International Airport to Syracuse Hancock International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $170–950
Flights from Piedmont Triad International Airport to Syracuse Hancock International Airport via Reagan Washington
- Ave. Duration
- 5h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–850
Flights from Piedmont Triad International Airport to Syracuse Hancock International Airport via Chicago O'Hare
- Ave. Duration
- 6h 28m
- When
- Every day
- Estimated price
- $250–1,200
Flights from Charlotte Douglas International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $150–850
Flights from Charlotte Douglas International Airport to Syracuse Hancock International Airport via Philadelphia
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $160–900
Flights from Charlotte Douglas International Airport to Syracuse Hancock International Airport via Reagan Washington
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $150–850
Flights from Raleigh-Durham International Airport to Syracuse Hancock International Airport via Philadelphia
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $120–700
Flights from Raleigh-Durham International Airport to Syracuse Hancock International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $140–800
Flights from Charlotte Douglas International Airport to Rochester
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $140–800
Flights from Charlotte Douglas International Airport to Rochester via Reagan Washington
- Ave. Duration
- 4h 5m
- When
- Saturday
- Estimated price
- $150–850
- Website
- united.com
Flights from Piedmont Triad International Airport to Syracuse Hancock International Airport via Washington Dulles
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $140–850
Flights from Piedmont Triad International Airport to Syracuse Hancock International Airport via Chicago O'Hare
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $250–1,200
Flights from Charlotte Douglas International Airport to Syracuse Hancock International Airport via Washington Dulles
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $150–850
Flights from Raleigh-Durham International Airport to Syracuse Hancock International Airport via Washington Dulles
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $120–700
Flights from Charlotte Douglas International Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $140–800
Flights from Piedmont Triad International Airport to Ithaca Tompkins Regional Airport via Washington Dulles
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $75–460
- Website
- delta.com
Flights from Piedmont Triad International Airport to Syracuse Hancock International Airport via Atlanta
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Piedmont Triad International Airport to Syracuse Hancock International Airport via New York La Guardia
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $160–900
Flights from Piedmont Triad International Airport to Syracuse Hancock International Airport via Detroit
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Charlotte Douglas International Airport to Syracuse Hancock International Airport via New York La Guardia
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $170–900
Flights from Raleigh-Durham International Airport to Syracuse Hancock International Airport via New York La Guardia
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $130–750
- Website
- southwest.com
Flights from Charlotte Douglas International Airport to Rochester via Baltimore
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $150–850
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 43m
- When
- Monday, Friday, and Wednesday
- Estimated price
- $260–1,700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from High Point to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 11h 41m
- Frequency
- Twice daily
- Estimated price
- $160–340
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Syracuse Regional Transportation Center
- Ave. Duration
- 5h 39m
- Frequency
- 4 times a day
- Estimated price
- $85–190
- Website
- Amtrak
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $24–55
- Website
- Amtrak
Train from Greensboro to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 11h 13m
- Frequency
- Twice daily
- Estimated price
- $150–330
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Albany-Rensselaer Amtrak Station
- Ave. Duration
- 2h 31m
- Frequency
- Hourly
- Estimated price
- $40–95
- Website
- Amtrak
Train from Albany-Rensselaer Amtrak Station to Syracuse Regional Transportation Center
- Ave. Duration
- 2h 46m
- Frequency
- 5 times a day
- Estimated price
- $45–100
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
Train from Albany-Rensselaer Amtrak Station to Syracuse Regional Transportation Center
- Ave. Duration
- 2h 39m
- Frequency
- Once daily
- Estimated price
- $40–190
- Website
- VIA Rail
- Escape
- $40–110
- Business
- $70–180
- Business Plus
- $85–190
- Economy
- $45–120
- Economy Plus
- $50–130
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Winston-Salem, NC to New York, NY
- Ave. Duration
- 11h 15m
- Frequency
- 3 times a day
- Estimated price
- $80–110
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $80–110
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from New York to Syracuse
- Ave. Duration
- 4h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–180
- Website
- Trailways
- Schedules at
- Trailways
- Saver
- $40–170
- Flexible
- $80–180
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $11–22
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Durham
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $12–23
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $11–22
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Newark Penn Station
- Ave. Duration
- 13h 25m
- Frequency
- Once daily
- Estimated price
- $85–170
- Website
- Greyhound
Bus from Newark Penn Station to Syracuse Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Greensboro Bus Stop
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- $4–8
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Ithaca to Syracuse Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a week
- Estimated price
- $9–16
- Schedules at
- Flixbus USA
Bus from Newark Penn Station to Syracuse Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a day
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
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More Questions & Answers
Winston-Salem to Syracuse bus services, operated by Wanda Coach, arrive at New York, NY station.
Winston-Salem to Syracuse train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Winston-Salem to Syracuse is 621 miles. It takes approximately 12h 21m to drive from Winston-Salem to Syracuse.
Book your Winston-Salem to Syracuse bus tickets online with Omio.
There are 94+ hotels available in Syracuse.















