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How to get fromWinston-Salem to Tupeloby plane, car, bus (Greyhound, Flixbus), bus, or bus (Greyhound)

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There are 7 ways to get from Winston-Salem to Tupelo by plane, car, bus (Greyhound, Flixbus), bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Piedmont Triad International Airport to Golden Triangle Regional Airport, drive

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Golden Triangle Regional Airport (GTR)plane plane GSO - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    6h 49m
    $110–500

  2. Bus via Charlotte

    cheapest
    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Atlanta Downtownbus bus
    3. Take the bus from Atlanta Bus Station to Tupelobus bus
    13h 38m
    $107–167

  3. Drive  581.9 mi

    1. Drive from Winston-Salem to Tupelocar car 581.9 mi
    10h 19m
    $107–154

  4. Bus to Charlotte Douglas International Airport, fly to Birmingham–Shuttlesworth International Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Birmingham–Shuttlesworth International Airport (BHM)plane plane CLT - BHM
    3. Drive from Birmingham-Airport-BHM to Tupelocar car
    6h 57m
    $151–816

  5. Bus to Charlotte Douglas International Airport, fly to Northwest Alabama Regional Airport, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Northwest Alabama Regional Airport (MSL)plane plane CLT - MSL
    3. Drive from Northwest Alabama Regional Airport (MSL) to Tupelocar car
    6h 40m
    $172–598

  6. Bus to Charlotte Douglas International Airport, fly to Huntsville International Airport-Carl T Jones Field, drive

    1. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane CLT - HSV
    3. Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar car
    7h 5m
    $120–611

  7. Bus (Greyhound)

    1. Take the bus from Winston Salem(Trans Center) to Atlanta Bus Stationbus bus Greyhound US0670
    2. Take the bus from Atlanta Bus Station to Tupelobus bus Greyhound US0610
    13h 54m
    $114–175

Piedmont Triad International Airport (GSO) to Golden Triangle Regional Airport (GTR) flights

Calendar15Weekly Planes
Duration5h 44mAverage Duration
Ticket$80Cheapest Price
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Comparing Your Travel Options

Map of how to get from Winston-Salem to Tupelo.ExpandLaunch map view
  • Distance: 609.4 mi
  • Duration: 6h 49m

What companies run services between Winston-Salem, NC, USA and Tupelo, MS, USA?

You can take a bus from Winston Salem(Trans Center) to Tupelo via Charlotte Bus Station, Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and Tupelo in around 13h 38m.

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