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How to get fromWisconsin to Buffaloby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Wisconsin to Buffalo by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from General Mitchell International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Buffalo Niagara International Airport (BUF)plane plane MKE - BUF
    5h 47m
    $114–704

  2. Bus

    cheapest
    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago to Clevelandbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    13h 40m
    $61–162

  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    14h 13m
    $153–499

  4. Drive  620.3 mi

    1. Drive from Milwaukee to Buffalocar car 620.3 mi
    10h 44m
    $114–164

  5. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    5h 17m
    $210–343

  6. Train to Chicago Midway International Airport, fly

    1. Take the train from Kenosha to Chicago OTCtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    5h 57m
    $171–325

  7. Bus via Detroit

    1. Take the bus from Milwaukee Intermodal Station to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Torontobus bus
    3. Take the bus from Toronto to Buffalobus bus
    19h 10m
    $105–163

Wisconsin to Buffalo by bus

Calendar14Weekly Buses
Duration13h 40mAverage Duration
Ticket$61Cheapest Price
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Comparing Your Travel Options

Map of how to get from Wisconsin to Buffalo.ExpandLaunch map view
  • Distance: 483.5 mi
  • Duration: 5h 47m

What companies run services between Wisconsin, USA and Buffalo, NY, USA?

Southwest Airlines, United Airlines, and two other airlines fly from General Mitchell International Airport (MKE) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Milwaukee Intermodal Station to Buffalo, NY via Chicago and Cleveland, OH in around 13h 40m.

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