There are 10 ways to get from Wisconsin to Des Moines by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from General Mitchell International Airport
best- Fly from General Mitchell International Airport (MKE) to Des Moines (DSM)plane MKE - DSM
5h 12m$90–475Drive 354.8 mi
cheapest- Drive from Milwaukee to Des Moinescar 354.8 mi
6h 23m$65–94Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus Greyhound US0150
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
9h 5m$74–113Train, bus via Saint Paul
- Take the train from Milwaukee to St. Paul-Minneapolistrain Borealis / ...
- Take the bus from Saint Paul Union Depot to Des Moinesbus Greyhound US0156
11h 22m$219–339Bus to Chicago O'Hare International Airport, fly
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane ORD - DSM
4h 29m$96–334Bus to Minneapolis–Saint Paul International Airport, fly
- Take the bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomingtonbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Des Moines (DSM)plane MSP - DSM
4h 37m$97–433Train to Chicago Midway International Airport, fly
- Take the train from Kenosha to Chicago OTCtrain
- Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane MDW - DSM
5h 12m$87–446Train, bus
- Take the train from Milwaukee to Chicago Union Stationtrain Hiawatha Service / ...
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
9h 8m$107–162Bus via Airport
- Take the bus from Milwaukee Mitchell Airport to Chicago Bus Stationbus FlixBus 2548 / ...
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
10h 52m$75–112Train, bus #2
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg to Des Moinesbus
11h$167–267
Wisconsin to Des Moines by bus
Comparing Your Travel Options
The cheapest way to get from Wisconsin to Des Moines is to drive which costs $65 - $95 and takes 6h 23m.
The fastest way to get from Wisconsin to Des Moines is to bus and fly which takes 4h 29m and costs $95 - $340.
No, there is no direct bus from Wisconsin station to Des Moines. However, there are services departing from Milwaukee Intermodal Station and arriving at Des Moines via Chicago Bus Station. The journey, including transfers, takes approximately 9h 5m.
The distance between Wisconsin and Des Moines is 325 miles. The road distance is 356.9 miles.
The best way to get from Wisconsin to Des Moines without a car is to bus which takes 9h 5m and costs $70 - $120.
It takes approximately 5h 12m to get from Wisconsin to Des Moines, including transfers.
Wisconsin to Des Moines bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
The best way to get from Wisconsin to Des Moines is to fly which takes 5h 12m and costs $90 - $480. Alternatively, you can bus, which costs $70 - $120 and takes 9h 5m.
Wisconsin to Des Moines bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Wisconsin to Des Moines is 357 miles. It takes approximately 6h 23m to drive from Wisconsin to Des Moines.
What companies run services between Wisconsin, USA and Des Moines, IA, USA?
Delta, United Airlines, and two other airlines fly from General Mitchell International Airport (MKE) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Milwaukee Intermodal Station to Des Moines via Chicago Bus Station in around 9h 5m.
- Website
- united.com
Flights from General Mitchell International Airport to Des Moines via Chicago O'Hare International Airport
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $70–450
Flights from General Mitchell International Airport to Des Moines via Denver
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $160–750
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $40–270
- Website
- delta.com
Flights from General Mitchell International Airport to Des Moines via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- $80–490
Flights from General Mitchell International Airport to Des Moines via Atlanta
- Ave. Duration
- 6h 8m
- When
- Every day
- Estimated price
- $150–750
Flights from Chicago O'Hare International Airport to Des Moines via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $50–310
Flights from Minneapolis–Saint Paul International Airport to Des Moines
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $50–370
- Website
- aa.com
Flights from General Mitchell International Airport to Des Moines via Chicago O'Hare International Airport
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $70–450
Flights from General Mitchell International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 39m
- When
- Monday, Thursday, and Sunday
- Estimated price
- $160–750
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $40–270
- Website
- southwest.com
Flights from General Mitchell International Airport to Des Moines via Chicago Midway International Airport
- Ave. Duration
- 5h 33m
- When
- Monday to Wednesday
- Estimated price
- $70–460
Flights from Chicago Midway International Airport to Des Moines
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $60–410
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to St. Paul-Minneapolis
- Ave. Duration
- 5h 52m
- Frequency
- 3 times a day
- Estimated price
- $170–280
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $85–140
- Website
- Amtrak
- Phone
- +1 312-696-3872
- Website
- Metra
Train from Kenosha to Chicago OTC
- Ave. Duration
- 1h 42m
- Frequency
- Every 3 hours
- Estimated price
- $6–8
- Website
- Metra
- Adult
- $6–8
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- $15–24
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $60–90
- Website
- Greyhound
Bus from Saint Paul Union Depot to Des Moines
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $60–90
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $60–90
- Website
- Greyhound
Bus from Galesburg to Des Moines
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
Bus from Milwaukee Mitchell Airport to Chicago Bus Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $13–20
- Schedules at
- Flixbus USA
- Phone
- (866) 912 6224
- [email protected]
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
- Phone
- +1 414-266-4409
- [email protected]
- Website
- Badger Bus
Bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomington
- Ave. Duration
- 1h 50m
- Frequency
- Twice a week
- Estimated price
- $26–35
- Website
- Badger Bus
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Booking & Getting There
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