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How to get fromWisconsin to Great Smoky Mountainsby bus, plane, car, or train

Find Transport to Great Smoky Mountains

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There are 10 ways to get from Wisconsin to Great Smoky Mountains by bus, plane, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Chicago O'Hare International Airport, fly to Mcghee Tyson Airport, drive

    best
    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    6h 15m
    $158–707

  2. Bus to Chicago O'Hare International Airport, fly to Asheville Regional Airport, drive

    cheapest
    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    3. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    6h 40m
    $107–383

  3. Bus, drive

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Union Station to Toledobus bus
    3. Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    26h 16m
    $198–322

  4. Train, bus, drive

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    35h 34m
    $361–809

  5. Drive  671 mi

    1. Drive from Milwaukee to Great Smoky Mountainscar car 671 mi
    12h 39m
    $123–177

  6. Train to Chicago Midway International Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from Kenosha to Chicago OTCtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Mcghee Tyson Airport (TYS)plane plane MDW - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    6h 57m
    $169–929

  7. Bus to Minneapolis–Saint Paul International Airport, fly to Mcghee Tyson Airport, drive

    1. Take the bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomingtonbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Mcghee Tyson Airport (TYS)plane plane MSP - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 17m
    $239–1,156

  8. Bus to Chicago O'Hare International Airport, fly to Greenville–Spartanburg International Airport, drive

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    3. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    7h 55m
    $152–576

  9. Bus to Chicago O'Hare International Airport, fly to Chattanooga Metropolitan Airport, drive

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Chattanooga Metropolitan Airport (CHA)plane plane ORD - CHA
    3. Drive from Chattanooga Metropolitan Airport (CHA) to Great Smoky Mountainscar car
    8h 17m
    $115–401

  10. Bus, drive via Columbus

    1. Take the bus from Milwaukee Intermodal Station to Columbusbus bus
    2. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    4. Drive from New Leicester Hwy at Walgreens to Great Smoky Mountainscar car
    27h 31m
    $171–274

Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) flights

Calendar87Weekly Planes
Duration1h 57mAverage Duration
Ticket$111Cheapest Price
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Comparing Your Travel Options

Map of how to get from Wisconsin to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 616.2 mi
  • Duration: 6h 15m

What companies run services between Wisconsin, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Wisconsin to Great Smoky Mountains. However, you can take the bus to O'Hare International Airport - Terminal 2 Departures, walk to Chicago O'Hare International Airport (ORD) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Milwaukee Intermodal Station to Great Smoky Mountains via Chicago Bus Station, Chicago Union Station, Toledo Bus Stop, Winston Salem(Trans Center), and Asheville, NC in around 26h 16m.

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