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How to get fromWise to Winston-Salemby car, shuttle, bus, or plane

Find Transport to Winston-Salem

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There are 6 ways to get from Wise to Winston-Salem by car, shuttle, bus, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, shuttle, bus

    best
    1. Drive from Wise to Black Bear Resortcar car
    2. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    3. Take the bus from Boone to Baptist Hospitalbus bus
    6h 34m
    $131–152

  2. Drive 187.8 mi

    cheapest
    1. Drive from Wise to Winston-Salemcar car 187.8 mi
    3h 36m
    $35–50

  3. Drive, fly

    1. Drive from Wise to Tri-Cities-Regional-Airport-TRIcar car
    2. Fly from Tri-Cities Regional Tn/Va Airport (TRI) to Piedmont Triad International Airport (GSO)plane plane TRI - GSO
    6h 4m
    $89–477

  4. Drive, shuttle, bus via Tri-Cities Regional Airport (TRI)

    1. Drive from Wise to Tri Cities Airportcar car
    2. Take a shuttle bus from Tri Cities Airport to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from Boone to Baptist Hospitalbus bus
    7h 19m
    $194–213

  5. Drive, bus

    1. Drive from Wise to Bristol Exit 5 Park & Ride Lotcar car
    2. Take the bus from Park and Ride Lot at I-81 Exit 5 to Rural King Shopping Centerbus bus
    3. Take the bus from Wytheville to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    8h 20m
    $64–175

  6. Drive, shuttle, bus via Boone

    1. Drive from Wise to Black Bear Resortcar car
    2. Take a shuttle bus from Black Bear Resort to Boots Off Bungalow, Booneshuttle bus
    3. Take the bus from Boone to Baptist Hospitalbus bus
    6h

Tri-Cities Regional Tn/Va Airport (TRI) to Piedmont Triad International Airport (GSO) flights

Calendar62Weekly Planes
Duration4h 7mAverage Duration
Ticket$64Cheapest Price
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Questions & Answers

Map of how to get from Wise to Winston-Salem.ExpandLaunch map view
  • Distance: 209.8 mi
  • Duration: 6h 34m

What companies run services between Wise, VA, USA and Winston-Salem, NC, USA?

There is no direct connection from Wise to Winston-Salem. However, you can drive to Black Bear Resort, take the shuttle to Boone, walk to Boone, then take the bus to Baptist Hospital. Alternatively, you can drive from Wise to Winston-Salem in around 3h 36m.

Airlines
Bus operators

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