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How to get fromWorcester to Buffaloby bus, plane, bus (Greyhound), train (Amtrak), car, or bus (Flixbus)

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There are 8 ways to get from Worcester to Buffalo by bus, plane, bus (Greyhound), train (Amtrak), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from Worcester Union Station to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    5h 18m
    $102–644

  2. Bus

    cheapest
    1. Take the bus from Worcester to Springfieldbus bus Ppb 6713 / ...
    2. Take the bus from Springfield Union Station to Buffalobus bus Greyhound US0171
    10h 20m
    $74–118

  3. Train (Amtrak)

    1. Take the train from Worcester Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    11h 44m
    $248–518

  4. Drive  415.8 mi

    1. Drive from Worcester to Buffalocar car 415.8 mi
    7h 15m
    $76–110

  5. Fly Worcester Regional Airport to Buffalo Niagara International Airport

    1. Fly from Worcester Regional Airport (ORH) to Buffalo Niagara International Airport (BUF)plane plane ORH - BUF
    9h 1m
    $92–580

  6. Bus to Boston Logan Airport, fly to Rochester, bus

    1. Take the bus from Worcester Union Station to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 49m
    $146–808

  7. Bus to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Worcester to New Yorkbus bus
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    7h 53m
    $143–791

  8. Bus via Ithaca

    1. Take the bus from Worcester Union Station to Albany Bus Terminal, NYbus bus
    2. Take the bus from Albany Bus Terminal, NY to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    13h 4m
    $76–136

Worcester to Buffalo by bus

Calendar7Weekly Buses
Duration10h 20mAverage Duration
Ticket$74Cheapest Price
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Comparing Your Travel Options

Map of how to get from Worcester to Buffalo.ExpandLaunch map view
  • Distance: 448.7 mi
  • Duration: 5h 18m

What companies run services between Worcester, MA, USA and Buffalo, NY, USA?

You can take a bus from Worcester to Buffalo via Springfield and Springfield Union Station in around 10h 20m. Alternatively, Amtrak operates a train from Worcester Union Station to Buffalo Depew Station once daily. Tickets cost $240–380 and the journey takes 10h 23m.

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