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How to get fromWorcester to Knoxvilleby bus, plane, car, bus (Greyhound), or train

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There are 12 ways to get from Worcester to Knoxville by bus, plane, car, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to Mcghee Tyson Airport

    best
    1. Take the bus from Worcester Union Station to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Mcghee Tyson Airport (TYS)plane plane BOS - TYS
    5h 19m
    $212–845

  2. Bus to Boston Logan Airport, fly to Asheville Regional Airport, drive

    cheapest
    1. Take the bus from Worcester Union Station to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Asheville Regional Airport (AVL)plane plane BOS - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    7h 7m
    $109–470

  3. Bus via New York

    1. Take the bus from Worcester to New Yorkbus bus Ppb 5725 / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    17h 6m
    $220–346

  4. Drive 872 mi

    1. Drive from Worcester to Knoxvillecar car 872 mi
    15h 18m
    $160–230

  5. Fly Worcester Regional Airport to Mcghee Tyson Airport

    1. Fly from Worcester Regional Airport (ORH) to Mcghee Tyson Airport (TYS)plane plane ORH - TYS
    11h 12m
    $197–822

  6. Bus to Bradley International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Worcester to Hartfordbus bus
    2. Fly from Bradley International Airport (BDL) to Mcghee Tyson Airport (TYS)plane plane BDL - TYS
    7h 24m
    $209–858

  7. Bus to Theodore Francis Green State Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Worcester Union Station to Providencebus bus
    2. Fly from Theodore Francis Green State Airport (PVD) to Mcghee Tyson Airport (TYS)plane plane PVD - TYS
    7h 44m
    $209–795

  8. Bus to Laguardia Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Worcester to New Yorkbus bus
    2. Fly from Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS)plane plane LGA - TYS
    7h 45m
    $255–1,016

  9. Bus

    1. Take the bus from Worcester Union Station to Port Authority Bus Terminalbus bus Boston
    2. Take the bus from New York to Knoxvillebus bus Nyc
    17h 7m
    $209–302

  10. Bus #2

    1. Take the bus from Worcester, MA - Union Station to New York, NY - 1st Avenue between East 38th and 39th Streetsbus bus Boston
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    17h 16m
    $193–287

  11. Bus, train

    1. Take the bus from Worcester Union Station to New Haven Bus Stopbus bus
    2. Take the train from New Haven to Grand Central Terminaltrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    18h 36m
    $220–315

  12. Train, bus

    1. Take the train from Worcester Union Station to Springfieldtrain train
    2. Take the train from Springfield to New Haventrain train
    3. Take the train from New Haven to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    19h 28m
    $191–843

Boston Logan Airport (BOS) to Mcghee Tyson Airport (TYS) flights

Calendar85Weekly Planes
Duration4h 43mAverage Duration
Ticket$152Cheapest Price
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Questions & Answers

Map of how to get from Worcester to Knoxville.ExpandLaunch map view
  • Distance: 886.9 mi
  • Duration: 5h 19m

What companies run services between Worcester, MA, USA and Knoxville, TN, USA?

You can take a bus from Worcester to Knoxville via New York, 42 St-Times Square, Canal St, New York, and Knoxville in around 17h 6m. Alternatively, Delta, American Airlines, and two other airlines fly from Worcester Regional Airport (ORH) to Mcghee Tyson Airport (TYS) 3 times a day.

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