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How to get fromWorcester to Louisvilleby bus, plane, train, bus (Greyhound, Flixbus), car, or bus (Greyhound, Amtrak)

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There are 12 ways to get from Worcester to Louisville by bus, plane, train, bus (Greyhound, Flixbus), car, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to Louisville International Airport

    best
    1. Take the bus from Worcester Union Station to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF)plane plane BOS - SDF
    6h 13m
    $129–679

  2. Fly Worcester Regional Airport to Louisville International Airport

    cheapest
    1. Fly from Worcester Regional Airport (ORH) to Louisville International Airport (SDF)plane plane ORH - SDF
    8h 18m
    $123–605

  3. Train, bus

    1. Take the train from Worcester Union Station to Cleveland Amtraktrain train Lake Shore Limited
    2. Take the bus from Cleveland Ohio Greyhound Station to Louisville, KY Bus Stationbus bus Cleveland
    22h 9m
    $240–500

  4. Bus

    1. Take the bus from Worcester Union Station to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Cincinnatibus bus
    3. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    23h 22m
    $153–301

  5. Drive 899.2 mi

    1. Drive from Worcester to Louisvillecar car 899.2 mi
    16h 13m
    $165–237

  6. Train to Bradley International Airport, fly to Louisville International Airport

    1. Take the train from Worcester Union Station to Springfieldtrain train
    2. Fly from Bradley International Airport (BDL) to Louisville International Airport (SDF)plane plane BDL - SDF
    7h 35m
    $133–652

  7. Bus to Theodore Francis Green State Airport, fly to Louisville International Airport

    1. Take the bus from Worcester Union Station to Providencebus bus
    2. Fly from Theodore Francis Green State Airport (PVD) to Louisville International Airport (SDF)plane plane PVD - SDF
    8h 49m
    $475–829

  8. Bus to Laguardia Airport, fly to Louisville International Airport

    1. Take the bus from Worcester, MA - Union Station to New York, NY - 1st Avenue between East 38th and 39th Streetsbus bus
    2. Fly from Laguardia Airport (LGA) to Louisville International Airport (SDF)plane plane LGA - SDF
    8h 53m
    $189–832

  9. Bus to Laguardia Airport, fly to Blue Grass Airport, drive

    1. Take the bus from Worcester, MA - Union Station to New York, NY - 1st Avenue between East 38th and 39th Streetsbus bus
    2. Fly from Laguardia Airport (LGA) to Blue Grass Airport (LEX)plane plane LGA - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    8h 46m
    $251–1,148

  10. Bus to Boston Logan Airport, fly to Covington, bus

    1. Take the bus from Worcester Union Station to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Covington (CVG)plane plane BOS - CVG
    3. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    8h 42m
    $419–1,073

  11. Train, bus via Indianapolis

    1. Take the train from Worcester Union Station to Toledotrain train
    2. Take the bus from Toledo to Indianapolis, INbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    24h 37m
    $281–596

  12. Bus via Indianapolis

    1. Take the bus from Worcester Union Station to Port Authority Bus Terminalbus bus
    2. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    25h
    $168–335

Worcester to Louisville by train, foot, and bus

Calendar7Weekly Services
Duration22h 9mAverage Duration
Ticket$240Cheapest Price
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Questions & Answers

Map of how to get from Worcester to Louisville.ExpandLaunch map view
  • Distance: 877.6 mi
  • Duration: 6h 13m

What companies run services between Worcester, MA, USA and Louisville, KY, USA?

You can take a bus from Worcester Union Station to Louisville, KY Bus Station via Newark Penn Station, Cincinnati, Vine St & Martin Luther King Dr, Race St & Court St, and Cincinnati - Downtown in around 23h 22m. Alternatively, American Airlines, JetBlue Airways, and Southwest Airlines fly from Worcester Regional Airport (ORH) to Louisville International Airport (SDF) twice daily.

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