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How to get fromWorcester to Mayo Clinicby bus, plane, bus (Greyhound, Flixbus), train, or car

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There are 11 ways to get from Worcester to Mayo Clinic by bus, plane, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to Rochester

    best
    1. Take the bus from Worcester Union Station to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (RST)plane plane BOS - RST
    8h 59m
    $108–555

  2. Bus

    1. Take the bus from Worcester Union Station to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    30h 23m
    $246–408

  3. Train, bus via Madison

    1. Take the train from Worcester Union Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    31h 12m
    $385–768

  4. Drive 1,288.8 mi

    1. Drive from Worcester to Mayo Cliniccar car 1,288.8 mi
    21h 51m
    $236–340

  5. Bus to Bradley International Airport, fly to Rochester

    1. Take the bus from Worcester to Hartfordbus bus
    2. Fly from Bradley International Airport (BDL) to Rochester (RST)plane plane BDL - RST
    9h 21m
    $116–548

  6. Bus to Theodore Francis Green State Airport, fly to Rochester

    1. Take the bus from Worcester Union Station to Providencebus bus
    2. Fly from Theodore Francis Green State Airport (PVD) to Rochester (RST)plane plane PVD - RST
    10h 29m
    $115–525

  7. Bus to Boston Logan Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Worcester Union Station to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Minneapolis–Saint Paul International Airport (MSP)plane plane BOS - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 36m
    $399–1,027

  8. Bus to Bradley International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Worcester to Hartfordbus bus
    2. Fly from Bradley International Airport (BDL) to Minneapolis–Saint Paul International Airport (MSP)plane plane BDL - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 47m
    $187–690

  9. Bus to Theodore Francis Green State Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Worcester Union Station to Providencebus bus
    2. Fly from Theodore Francis Green State Airport (PVD) to Minneapolis–Saint Paul International Airport (MSP)plane plane PVD - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 15m
    $186–677

  10. Bus to Boston Logan Airport, fly to Dane County Regional Airport-Truax Field, bus

    1. Take the bus from Worcester Union Station to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Dane County Regional Airport-Truax Field (MSN)plane plane BOS - MSN
    3. Take the bus from Madison to Rochesterbus bus
    11h 48m
    $199–802

  11. Train, bus

    1. Take the train from Worcester Union Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    32h 10m
    $468–948

Worcester to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration30h 23mAverage Duration
Ticket$246Cheapest Price
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Questions & Answers

Map of how to get from Worcester to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,139.3 mi
  • Duration: 8h 59m

What companies run services between Worcester, MA, USA and Mayo Clinic, MN, USA?

You can take a bus from Worcester Union Station to Mayo Clinic via Newark Penn Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 30h 23m.

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